Relationship between erectile dysfunction metabolic syndrome

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* The current video summarizes and critical analyzes available evidence from the first reports to a recently updated meta-analysis [1]. Data derived from a meta-analytic approach, including 25 studies and 18,237 subjects showed that MetS was associated with a significant increased risk of ED when either unadjusted or adjusted data were considered. However, fully adjusted models showed that MetS category did not provide better information when compared to the specific components considered in the algorithm [1].






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Description​

Data emerging from the last few years have questioned the specific role played by the metabolic syndrome (MetS) versus its single components in the pathogenesis of erectile dysfunction (ED). The current video summarizes and critical analyzes available evidence from the first reports to a recently updated meta-analysis [1]. Data derived from a meta-analytic approach, including 25 studies and 18,237 subjects showed that MetS was associated with a significant increased risk of ED when either unadjusted or adjusted data were considered. However, fully adjusted models showed that MetS category did not provide better information when compared to the specific components considered in the algorithm [1]. Similar results have been reported for the possible relationship between MetS and long-term cardiovascular risk [2,3]. MetS is also associated with reduced testosterone levels, but its contribution to MetS-associated ED is limited [4]. Despite this evidence identifying and managing the individual MetS components remains crucial considering their pivotal role in determining ED.
 

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