65 y/o | 165 lbs | 5’6” | ~10–12% BF
Recently transitioned from compounded cream → injectable TRT for first time.
Was on cream for just over 4 mos.
June 2025 (on cream; peak; applied 2h prior ):
Sept 2025 (cream; applied 12h prior):
Recently transitioned from compounded cream → injectable TRT for first time.
Was on cream for just over 4 mos.
- Reason: no noticeable sides, but DHT spiking and unstable serum levels.
- Current protocol (2 days): Test E in MCT oil, 11 units ED (~21 mg), ~150 mg/week total, subq microdosing (slin pin). Plan: 6 weeks → labs → add nandrolone decanoate in MCT oil, 50 mg/week for joint relief/inflammation.
June 2025 (on cream; peak; applied 2h prior ):
- TT: 1034 ng/dL
- Free T: 191.6 pg/mL (H)
- SHBG: 52
- DHT: 144 ng/dL (H)
- Estradiol: 46 pg/mL (H)
- LH: 2.4 / FSH: 4.2
- Prolactin: n/a
Sept 2025 (cream; applied 12h prior):
- TT: 318–459 ng/dL (
- Free T: 61.5–70.7 pg/mL (↓)
- SHBG: 36–39
- DHT: 122–145 ng/dL (still high)
- Free DHT: 9.32 pg/mL (H)
- Estradiol (ultrasensitive): 24 pg/mL (normalized)
- LH: 0.6–0.8 (L) / FSH: 1.0 (L) → HPTA suppressed
- Prolactin: 6.7–6.9 ng/mL
CBC / Hematology: - 6/30/25:
- RBC: 4.32 M/uL (ref 4.20–5.80)
- Hgb: 14.1 g/dL
- Hct: 42.4%
- 9/12/25:
- RBC: 4.22–4.26 M/uL (low end of normal)
- Hgb: 13.6 g/dL
- Hct: 40.5–41.4%
- On cream: supraphysiological TT/FT + elevated E2 + high DHT.
- By Sept: TT/FT crashed, gonadotropins suppressed, E2 normalized, but DHT stayed elevated.
- Prolactin baseline looks safe to trial low-dose nandrolone.
- Experiences pivoting from transdermal to daily microdosed injections (stability, labs, symptom changes)?
- Anyone add low-dose Deca (50–100 mg/week) for joints — what benefits/downsides did you see?
- Best strategies you’ve used to keep DHT in check post-cream transition?
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