Pregnenolone... considering adding to TRT regimen...

BillyJ03z · Apr 24, 2018

Have very low DHEA-s 90 (70-495) and Thyroid issues (in range low T4, in range low free T4, in range upper level range Ft3, in range lower Level total T3)...

I've tried using DHEA but it shot my E2 into the 100's.... Looking to use Pregnenelone to raise Preg, DHEA levels, etc...

What are the recommended starting doses when starting pregnenolone? any brand/type recommendations...?

Systemlord · Apr 24, 2018

It depends on the severity of the deficiency. I tried 30mg Pregnenolone and became very groggy and heart rate increased to a point sleep became impossible, it wore off 6 hours later. Consider time release Pregnenolone.

BillyJ03z · Apr 25, 2018

Systemlord said:
It depends on the severity of the deficiency. I tried 30mg Pregnenolone and became very groggy and heart rate increased to a point sleep became impossible, it wore off 6 hours later. Consider time release Pregnenolone.

I was thinking of trying 10mg pregnenolone sublingual to start slow... IMHO... my DHEAs is in the toilet so my Preg has to be there as well.. I feel that I am Hypo but I don't if it is due to TRT, or was existing and made worse by TRT...

1Draw · May 6, 2018

Suggest you have full thyroid panel done especially T3 and Reverse T3. Testerone doesn’t affect thyroid but low thyroid can have a negative impact on T.
Here is a good explanation
https://www.restartmed.com/thyroid-symptoms-men/

BillyJ03z · May 6, 2018

1Draw said:
Suggest you have full thyroid panel done especially T3 and Reverse T3. Testerone doesn’t affect thyroid but low thyroid can have a negative impact on T.
Here is a good explanation
https://www.restartmed.com/thyroid-symptoms-men/

I have my Thyroid panel checked regularly and it always shows low in-range FT4 and upper in-range FT3 and a TSH over 3... Basically those numbers indicate I am hypo according to STTM... but I have also researched that exogenous Testosterone injections (TRT) does have an effect on Thyroid function and SHBG which in my case it suppresses/lowers... I already have that site bookmarked, great site...