madman
Super Moderator
Potential Cardiovascular and Metabolic Beneficial Effects of ω-3 PUFA in Male Obesity Secondary Hypogonadism Syndrome
Abstract: Long-chain ω-3 polyunsaturated fatty acids (PUFAs) are fundamental bio components of lipids and cell membranes. They are involved in the maintenance of cellular homeostasis and they are able to exert anti-inflammatory and cardioprotective actions. Thanks to their potential beneficial effects on the cardiovascular system, metabolic axis, and body composition, we have examined their action in subjects affected by male obesity secondary hypogonadism (MOSH) syndrome. MOSH syndrome is characterized by the presence of obesity associated with the alteration of sexual and metabolic functions. Therefore, this review article aims to analyze scientific literature regarding the possible benefits of ω-3 PUFA administration in subjects affected by MOSH syndrome. We conclude that there is strong evidence supporting ω-3 PUFA administration and/or supplementation for the treatment and management of MOSH patients.
5. Summary and Future Perspectives
In conclusion, there seems to be evidence that ω-3 PUFA consumption may be clinically beneficial in the treatment and clinical management of MOSH patients. The ability of ω-3 PUFAs to act on some pathological aspects of MOSH, such as obesity, inflammation, metabolic and cardiovascular disorders, coupled with their optimal safety profile, leads us to the postulation that ω-3 PUFA assumption could be a valuable tool in ameliorating the clinical manifestations of MOSH syndrome.
In pursuance to assess this conclusion in a definitive manner and in order to define the most advantageous dosage, randomized clinical trials on a large population sample are required. Moreover, it would be interesting and useful to conduct experimental studies exploring the possible effects of ω-3 PUFA consumption on hormone profile, on the sexual sphere (T concentrations), and on body composition.
Abstract: Long-chain ω-3 polyunsaturated fatty acids (PUFAs) are fundamental bio components of lipids and cell membranes. They are involved in the maintenance of cellular homeostasis and they are able to exert anti-inflammatory and cardioprotective actions. Thanks to their potential beneficial effects on the cardiovascular system, metabolic axis, and body composition, we have examined their action in subjects affected by male obesity secondary hypogonadism (MOSH) syndrome. MOSH syndrome is characterized by the presence of obesity associated with the alteration of sexual and metabolic functions. Therefore, this review article aims to analyze scientific literature regarding the possible benefits of ω-3 PUFA administration in subjects affected by MOSH syndrome. We conclude that there is strong evidence supporting ω-3 PUFA administration and/or supplementation for the treatment and management of MOSH patients.
5. Summary and Future Perspectives
In conclusion, there seems to be evidence that ω-3 PUFA consumption may be clinically beneficial in the treatment and clinical management of MOSH patients. The ability of ω-3 PUFAs to act on some pathological aspects of MOSH, such as obesity, inflammation, metabolic and cardiovascular disorders, coupled with their optimal safety profile, leads us to the postulation that ω-3 PUFA assumption could be a valuable tool in ameliorating the clinical manifestations of MOSH syndrome.
In pursuance to assess this conclusion in a definitive manner and in order to define the most advantageous dosage, randomized clinical trials on a large population sample are required. Moreover, it would be interesting and useful to conduct experimental studies exploring the possible effects of ω-3 PUFA consumption on hormone profile, on the sexual sphere (T concentrations), and on body composition.
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