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estradiol is also important for dopamine neurons which produce dopamine.. if half of your dopamine neurons will die due to multiple e2 crashes your brain simply won't be able to produce enough dopamine so that causes one to be moody, sad, no drive and so on.. also increased risk for parkinson disease.. wouldnt wish this on anyone and unless you take dopamine drugs you can't get rid of that mood state it's permanent unless brain can create new dopamine producing neurons
gyno and water retention is walk in the park compared to what damage too low e2 does to humans especially to males.

[QUOTE="lowe2sucks, post: 107521, member: 13891"] estradiol is also important for dopamine neurons which produce dopamine.. if half of your dopamine neurons will die due to multiple e2 crashes your brain simply won't be able to produce enough dopamine so that causes one to be moody, sad, no drive and so on.. also increased risk for parkinson disease.. wouldnt wish this on anyone and unless you take dopamine drugs you can't get rid of that mood state it's permanent unless brain can create new dopamine producing neurons gyno and water retention is walk in the park compared to what damage too low e2 does to humans especially to males. [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038