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I don't really have any insight on the senescense issue other than it may make sense to do a round of senolytics such as rapamycin and/or azithromycin before harvesting the stem cells, although I have no idea if that would help, but rapamycin is something that seems to make a lot of sense on an intermittent basis no matter what, something like 4-6mg every other week is a protocol many people use for general anti-aging.


Regarding food sensitivities, a good old-fashioned elimination diet seems like a good option and an accidental version of that is how I figured out that whey protien was a problem for me. At a minimum, eliminating all the high-risk foods for a while such as seed oils, wheat, eggs, processed foods, dairy (except for butter), legumes and most plant matter will go a long way to tell if that is part of the issue for you. Good luck with your journey.


I can understand Dr. C's concern with regulatory issues, but other Drs seem to use peptides with no problem, it seems reasonable to at least educate the patient as to the options, and a lot of other things like those in the Joint Issues thread have no regulatory issue.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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