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TRT and growth hormone have a synergistic effect. I would suggest you go with both. As well Sermorelin, is one of the weakest GHRHs. It has a very short 1/2 life of about 3 minutes. 3rd Generation GHRHs like modified GRF 1-29 have a longer half life of about 30 minutes. It is also recommended that you add a GHRP becasuse combined you get a much more synergism. In other words the efect on GH/IGF-1 levels is much greater.

500mcg/dose? From all the research I have read on doseing peptides the receptor site saturation dose is 1mcg/kg. Any more after that results in the law of deminishing results, very quickly. But simple math says 500mcg will get you 4 doses from a 2mg (2000mcg) vial. Is oral Sermorelin effective? Caveat emptor - Mayo Clinic reports that Sermorelin is only effective as an injection.

<blockquote data-quote="Deleted member 43589" data-source="post: 239259" data-attributes="member: 43589">TRT and growth hormone have a synergistic effect.&nbsp; I would suggest you go with both.&nbsp; As well Sermorelin, is one of the weakest GHRHs.&nbsp; It has a very short 1/2 life of about 3 minutes.&nbsp; 3rd Generation GHRHs like modified GRF 1-29 have a longer half life of about 30 minutes.&nbsp; It is also recommended that you add a GHRP becasuse combined you get a much more synergism.&nbsp; In other words the efect on GH/IGF-1 levels is much greater.500mcg/dose?&nbsp; From all the research I have read on doseing peptides the receptor site saturation dose is 1mcg/kg.&nbsp; Any more after that results in the law of deminishing results, very quickly. But simple&nbsp; math says 500mcg will get you 4 doses from a 2mg (2000mcg) vial.&nbsp; Is oral Sermorelin effective?&nbsp;&nbsp; Caveat emptor - Mayo Clinic reports that Sermorelin is only effective as an injection.</blockquote>

[QUOTE="Deleted member 43589, post: 239259, member: 43589"] TRT and growth hormone have a synergistic effect. I would suggest you go with both. As well Sermorelin, is one of the weakest GHRHs. It has a very short 1/2 life of about 3 minutes. 3rd Generation GHRHs like modified GRF 1-29 have a longer half life of about 30 minutes. It is also recommended that you add a GHRP becasuse combined you get a much more synergism. In other words the efect on GH/IGF-1 levels is much greater. 500mcg/dose? From all the research I have read on doseing peptides the receptor site saturation dose is 1mcg/kg. Any more after that results in the law of deminishing results, very quickly. But simple math says 500mcg will get you 4 doses from a 2mg (2000mcg) vial. Is oral Sermorelin effective? [B]Caveat emptor[/B] - Mayo Clinic reports that Sermorelin is only effective as an injection. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038