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Even if they can't be completely decoupled, being especially attentive to all the usual suspects for maximizing insulin sensitivity (e.g. Time restricted eating, minimum effective dose of carbs, encouraging Non Insulin Mediated Glucose Uptake, berberine, metformin, etc.) might well allow a fairly high IGF-1 level for enough time to have benefit. Also, if insulin returns to normal after a GH run that might also create a positive risk/reward for the GH. I'm just speculating but my basic point is that if GH provides benefits that nothing else does, then ruling it out based on a blanket statement that it is always a net negative for everyone seems like an overstatement of the risks.

On a related note, I recently had two major healing events, one for my back and one for one of my hips, and although I was/am using/doing many things, a GH peptide was one of the things which seemed to help the most during a very short period of use.