On Accutane: Looking for a Supplement that lowers LDL and increases HDL

[Ronnny]

I have taking fish oil. But does anybody know which supplement is helpful for good lipid panel?

I tried niacin 500mg, I get hot flush/red rash with it. But I think niacin very good for Lipid panel.

Currently I am on Testosterone cypionate and accunate for acne.My LDL and HDL both out of range in terms of bad side.

 

[captain]

Try wax matrix niacin. It didn't work as well for me as regular niacin but if you can't handle regular niacin it's the next best thing.

 

[Ronnny]

I ordered some No-flush/ flush free niacin. I will try to see if that I can handle or not.

@ captain. is wax matrix niacin readily available or prescription niacin?

 

[Ronnny]

I try one vitamin that has Folic Acid-B6-B12 combined ( prescription)

Name: Folinic plus.

 

[captain]

OTC Wax Matrix Niacin
The no flush doesn't do anything for Cholesterol. Add some CoQ10 and good Krill Oil. I like Viva krill Oil but it's expensive.

 

[Vince]

no-flush niacin generates virtually no free nicotinic acid, and has little or no effect on HDL. No-flush niacin lives up to the no-flush part of its name because it isn't providing the body with any niacin.

Ask the doctor: Is no-flush niacin as effective as other kinds of niacin? - Harvard Health

 

[Tommy Wall]

So no flush niacin is worthless or?

 

[Sean Mosher]

There's a Jarrows Red Yeast Rice with CoQ10 that i"m using that i like.
May be worth a shot.

 

[Nelson Vergel]

Cutis. 2014 Nov;94(5):234-8
Effects of oral isotretinoin on lipids and liver enzymes in acne patients.
Kızılyel O1, Metin MS, Elmas ÖF, Çayır Y, Aktaş A.

Abstract
Isotretinoin has been used to treat severe inflammatory acne that is resistant to antibiotics or topical agents; however, it also may cause alterations in lipids and liver enzymes. In this retrospective study, we evaluated changes in lipids and liver enzymes in 322 acne patients who had been treated with oral isotretinoin at our institution over a 3-year period. Each patient's medical records were evaluated to determine baseline triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels compared to levels recorded at 3 and 6 months following initiation of treatment with oral isotretinoin. Overall, statistically significant increases in TG and LDL levels were noted following treatment with isotretinoin (P<.001, respectively), while HDL levels were shown to decrease (P=.016). Although ALT levels also increased, the changes were not statistically significant increases in AST levels also were noted (P=.72). In our study, isotretinoin appeared to have a greater effect on lipids than liver enzymes. Dermatologists should not avoid isotretinoin use for appropriate indications, but close follow-up is important.

 

[Ronnny]

My dermatologist check my Triglyceride every month. Is the any difference between Krill oil and regular Omega-3 fish oil? Since both are fish oil.

is Krill oil more potent?

 

[captain]

There is differences in absorption and oxidation. I used fish oil for years and have use prescription fish oil. My labs look better on krill. The prescription fish oil didn't do anything. There is a possible fasting glucose increase taking high dose fish oil. I think its a 10% increase if I remember correctly. I don't know if Krill causes the same.