* Our findings suggest that the presence of OSA risk factors may alter the effect of TRT on OSA incidence, where TRT is associated with lower incidence in people without risk factors and higher incidence in people with risk factors.
INCIDENCE OF OBSTRUCTIVE SLEEP APNEA IN PATIENTS TAKING TESTOSTERONE REPLACEMENT THERAPY STRATIFIED BY OSA RISK FACTORS
Kathleen Li*, Rochester, NY; Thomas Chen, New York, NY; Parth Joshi,David Peters, Mineola, NY
INTRODUCTION AND OBJECTIVE
The relationship between hypogonadism, testosterone replacement therapy (TRT), and...
* Substantial evidence suggests that sleep disorders may impair testosterone levels, partially improved after specific treatments (for instance: positive airway pressure for OSA). On the other hand, appropriate indications for testosterone replacement therapy (TRT) can alleviate hypogonadism symptoms and cardiometabolic dysfunction, but may increase the risk of OSA, requiring careful management. This narrative review highlights the importance of a holistic approach in managing sleep disorders, CVDs, and hormonal imbalances and emphasises the need for further research to improve...
How often should men on TRT check their hematocrit?
The standard monitoring schedule includes a baseline CBC before starting TRT, a recheck at 3 to 6 weeks, another at 3 months, and then at 6 and 12 months once stable. Any dose or formulation change resets the monitoring clock, requiring a recheck 4 to 6 weeks later. Men with risk factors for elevated hematocrit (sleep apnea, smoking, COPD, or a history of clotting) should check more frequently: every 3 months until the trend is stable.
* The monitoring schedule, the intervention ladder, and the attention...
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