There is no such thing as an "ideal number" when it comes to measuring estradiol. I feel good when my e2 is anywhere from 25 to 38. I attribute,that to the fact that my total testosterone may vary a bit as well. My doctor and I reject any hard and fast rules when it comes to estradiol management. That means not getting caught in the "my e2 has to be in the 20-30 range no matter what" trap. If my testosterone is higher, my estradiol can ride higher. Symptoms, informed by labs, help in the process. You may be in need of Anastrozole, depressed libido certainly raises the possibility. What is your total testoterone? What are your doctor's thoughts on estradiol management?