Normalization of testosterone level after testosterone replacement therapy could decrease risk of ca

Troutman

New Member
Guys, more good news regarding TRT. A new study has just come out supporting TRT and cardiovascular health. Here's an excerpt:

In the study, researchers from Kansas City VA Medical Centre in Kansas City, USA, examined the effect of TRT on cardiovascular outcomes by comparing incidences of heart attack, stroke, and all-cause mortality among different sub-populations of treated and untreated patients. The study used the largest cohort of patients and the longest follow-up for TRT to date.

Dr Barua went on to say: "In this study of men, without previous history MI or stroke, with low testosterone levels, normalization of testosterone levels using TRT is associated with lower mortality, fewer MIs, and strokes. This is the first study to demonstrate that significant benefit is observed only if the dose is adequate to normalize the testosterone levels."


As noted in the study, its uses the largest cohort to date and the longest follow-up period. This study should carry weight and needs to be acknowledged by the medical and regulatory community.

Here's the link: http://www.eurekalert.org/pub_releases/2015-08/oup-not080415.php
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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