Hello everyone.
I'm a 53-year-old, obese male who has many of the classic low-t symptoms. Difficulty in obtaining/maintaining erections, constantly irritable, have a hard time getting to sleep, maintaining sleep, brain fog, poor memory and difficulty concentrating.
I read Jay Campbell's book and found out about Defy Medical. I paid extra and got some of the other tests in addition to the standard tests in order to get a baseline in the event that a physician wanted to prescribe medications/supplements.
Here are my key numbers
Total Testosterone: 332
Free Testosterone: 3.8 (LOW)
SHBG: 42.2
Estradiol (Sensitive) 19.9
DHT: 20 (LOW)
DHEA: 169.4
LH: 5.1
Prolactin: 10.3
Pregnenolone, MS: 39
PSA: 1.3
IGF-1: 100
T4 Free 1.37
T3 Free 3.1
TSH 2.930
A few days after getting my test results, I had a consultation with an Advance Practice NP at Defy and he prescribed the following:
T Cyp 200 mg/mL – 0.35 mL (70mg) IM/SQ twice a week.
HCG 500 IU SQ twice a week. To reverse/prevent testicular atrophy. Increase Free T.
Anastrozole 0.125 mg one by mouth twice a week. Hold for the first 4 weeks, then as needed. PRN per elevated E2 symptoms
DHEA 25 mg one by mouth every night. To Decrease SHBG and Raise Free T.
NDT 0.5 Grains (30 mg) (or T3/T4 equivalent 4.5/19 mcg) - One by mouth every AM, for two weeks. Then can increase to 1 Grain (60 mg) by mouth every AM, for two weeks. Then can increase to 1.5 Grain (90 mg) by mouth every AM, for two weeks. Then can increase to 2 Grain (120 mg) by mouth every AM, for two weeks. Can continue to titrate 0.5 Grains (30 mg) in intervals of 2 weeks or longer, per benefit and tolerance as discussed, STOPPING at a maximum of 3 Grains (180 mg). Stop titration if any hyperthyroid symptoms occur and go back to the previous dosage starting the next day. Take first thing in the morning upon waking, on empty stomach, at least 30, preferably 60 minutes before breakfast.
GABA Injectable, 10mL 100mg/ml inject 0.25ml-0.5ml every night. PRN - helps with sleep.
I am a strong believer in the concept of minimum effective dosing as well as the old adage "go low, start slow."
I absolutely disagree with supraphysiologic dosing unless it proves the only way to raise T. Therefore I informed the provider of my intention start very low and then work up. I also informed them of my desire to inject daily, subcutaneously. I sent a message via email to them to ask them if I can also change to T-Propinate.
Once my medication arrives from Empower Pharmacy, I will begin injecting 10mg of Test daily, subcutaneously. Once I conduct follow up testing my provider and I can adjust.
I know that many of you on this forum are extremely knowledgeable and I know nothing about T and am just starting out. However, I'm the one who has to live with my decisions as well as being able to sleep at night.
Based on my research, I feel that daily subcutaneous administration of T results in many added benefits such as more stable serum levels of testosterone, lower estradiol levels and most closely mimics natural physiological production of testosterone.(especially if used with T-prop) I also believe that this method is safer in terms of adverse events.
In the end, I can always increase my levels after follow-up lab testing.
I'm very impressed with the knowledge on this site and happy to be a new member. I will post my results and issues as they arise. Mostly, though, I will just read and learn.
Thank you in advance for any information that you can pass along to me about my numbers and/or plans.
I'm a 53-year-old, obese male who has many of the classic low-t symptoms. Difficulty in obtaining/maintaining erections, constantly irritable, have a hard time getting to sleep, maintaining sleep, brain fog, poor memory and difficulty concentrating.
I read Jay Campbell's book and found out about Defy Medical. I paid extra and got some of the other tests in addition to the standard tests in order to get a baseline in the event that a physician wanted to prescribe medications/supplements.
Here are my key numbers
Total Testosterone: 332
Free Testosterone: 3.8 (LOW)
SHBG: 42.2
Estradiol (Sensitive) 19.9
DHT: 20 (LOW)
DHEA: 169.4
LH: 5.1
Prolactin: 10.3
Pregnenolone, MS: 39
PSA: 1.3
IGF-1: 100
T4 Free 1.37
T3 Free 3.1
TSH 2.930
A few days after getting my test results, I had a consultation with an Advance Practice NP at Defy and he prescribed the following:
T Cyp 200 mg/mL – 0.35 mL (70mg) IM/SQ twice a week.
HCG 500 IU SQ twice a week. To reverse/prevent testicular atrophy. Increase Free T.
Anastrozole 0.125 mg one by mouth twice a week. Hold for the first 4 weeks, then as needed. PRN per elevated E2 symptoms
DHEA 25 mg one by mouth every night. To Decrease SHBG and Raise Free T.
NDT 0.5 Grains (30 mg) (or T3/T4 equivalent 4.5/19 mcg) - One by mouth every AM, for two weeks. Then can increase to 1 Grain (60 mg) by mouth every AM, for two weeks. Then can increase to 1.5 Grain (90 mg) by mouth every AM, for two weeks. Then can increase to 2 Grain (120 mg) by mouth every AM, for two weeks. Can continue to titrate 0.5 Grains (30 mg) in intervals of 2 weeks or longer, per benefit and tolerance as discussed, STOPPING at a maximum of 3 Grains (180 mg). Stop titration if any hyperthyroid symptoms occur and go back to the previous dosage starting the next day. Take first thing in the morning upon waking, on empty stomach, at least 30, preferably 60 minutes before breakfast.
GABA Injectable, 10mL 100mg/ml inject 0.25ml-0.5ml every night. PRN - helps with sleep.
I am a strong believer in the concept of minimum effective dosing as well as the old adage "go low, start slow."
I absolutely disagree with supraphysiologic dosing unless it proves the only way to raise T. Therefore I informed the provider of my intention start very low and then work up. I also informed them of my desire to inject daily, subcutaneously. I sent a message via email to them to ask them if I can also change to T-Propinate.
Once my medication arrives from Empower Pharmacy, I will begin injecting 10mg of Test daily, subcutaneously. Once I conduct follow up testing my provider and I can adjust.
I know that many of you on this forum are extremely knowledgeable and I know nothing about T and am just starting out. However, I'm the one who has to live with my decisions as well as being able to sleep at night.
Based on my research, I feel that daily subcutaneous administration of T results in many added benefits such as more stable serum levels of testosterone, lower estradiol levels and most closely mimics natural physiological production of testosterone.(especially if used with T-prop) I also believe that this method is safer in terms of adverse events.
In the end, I can always increase my levels after follow-up lab testing.
I'm very impressed with the knowledge on this site and happy to be a new member. I will post my results and issues as they arise. Mostly, though, I will just read and learn.
Thank you in advance for any information that you can pass along to me about my numbers and/or plans.
