New clinical trial of a male birth control gel (NES/T gel)

[madman]

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*Men make 1000 sperm per heartbeat!

* Normal sperm count = 15-200 million/mL

 

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The holy grail of hormonal male birth control? - ExcelMale - #1 TRT & Testosterone Forum | Expert-Moderated Men's Health Community

https://www.statnews.com/2022/11/16/male-birth-control-pregnancy-drug-development/ Fortunately, researchers think they are closer than ever to delivering on the holy grail of hormonal male birth control, with promising — if early — evidence of a contraceptive gel called NES/T and more products...

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ExcelMale - #1 TRT & Testosterone Forum | Expert-Moderated Men's Health Community

This discussion was led by Dr. Christina Wang who is an internationally recognized investigator in male reproductive medicine and biology and is a Professor of Medicine, Assistant Dean at the David Geffen School of Medicine at UCLA, and Site Director for the Clinical and Translational Science...

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ExcelMale - #1 TRT & Testosterone Forum | Expert-Moderated Men's Health Community

Abstract Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30–50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies, lifestyle factors (such as...

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post #6

TRT used as birth control? - ExcelMale - #1 TRT & Testosterone Forum | Expert-Moderated Men's Health Community

Hi everyone, I was thinking...If TRT stops the production of sperm, is it possible to use TRT as birth control? I take 20mg, subq, six days a week, 120mg total a week) and I'm 51 years old. It's a crazy question, but something I was thinking about. Thank you all!!

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[madman]

Thread 'Condoms and Vasectomies Aren’t Enough—Is a Male Birth Control Pill Next?'

Oct 11, 2025

* Several other reversible male birth-control methods are now in the clinical trial pipeline as well. The furthest along is NES/T, a combination of testosterone and the progestin medication Nestorone. Applied daily as a gel to the shoulders and upper arms, it is absorbed into the bloodstream through the skin. Like the YCT-529 pill, the gel targets sperm production, but it does so by increasing the amount of circulating testosterone and progestin—hormones that tell the brain to halt the production process. Researchers have just completed a larger, longer...

• madman
• male birth control; contraceptives/fertility
• Replies: 2
• Forum: Health & Wellness