Nelson Vergel's Top 10 Testosterone Commandments

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Nelson Vergel

Founder, ExcelMale.com
1.Have reasonable expectations. Testosterone is not a magic bullet.


2.Do not fall prey to testosterone booster scams.


3.Do not obsess about estradiol without testing it with right (sensitive) test.


4.Monitor your hematocrit every 2-3 months during first year of therapy. Donate blood if it reaches 52, but be careful with donations more frequent than every two months (low iron or ferritin).


5.Explore easier ways to inject like subcutaneous and shallow IM.


6.Never cycle TRT on and off.


7.You can’t change what you don’t measure. Monitor your blood tests and quality of life. Know your trends. Use DiscountedLabs.com, MyHealthGraphs.com & TRT Analyzer App.


8.Do not change more than one variable at a time. You will lose track of what works and what doesn’t.


9.Protect your fertility, testicles and upstream hormones (HCG)


10.Don’t stay behind in this evolving field. Register on ExcelMale.com


Nelson's Top Ten TRT Commandments.webp

 
Last edited:
Thanks for this. I'm looking to start HRT in January and a list like this is great.

Can you post a link to the app in the Play Store? I'm pretty sure I found the right one but just want to be sure.

Here: www.TRTData.com
 
Commandment 9
Upstream Hormones
.
I have watched your youtube video on this, do you have further information on all upstream hormones that shut down due to TRT & possible effects??
.
i.e. shutdown of cholesterol, progesterone etc, I understand the shutdown of LH & FSH but would like to look more in depth into this.
.
all info is greatly appreciated, I next meet with my Urologist on 14th Aug and would like to chat to him about these points
 
Commandment 9
Upstream Hormones
.
I have watched your youtube video on this, do you have further information on all upstream hormones that shut down due to TRT & possible effects??
.
i.e. shutdown of cholesterol, progesterone etc, I understand the shutdown of LH & FSH but would like to look more in depth into this.
.
all info is greatly appreciated, I next meet with my Urologist on 14th Aug and would like to chat to him about these points

Here is some evidence. We have little data beyond this paper.

Anabolic steroids and TRT decrease SHBG, DHEA, pregnenolone and progesterone in men.
 
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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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