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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Need help with T-Cypionate - Vials (Single vs. multiple - What do you guys use?)
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<blockquote data-quote="Cataceous" data-source="post: 255740" data-attributes="member: 38109"><p>Call BS on him.</p><p style="margin-left: 20px"><em>Low FT level, even in the presence of normal TT, is associated with ED severity in young men.</em></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/30349000/[/URL]</p><p style="margin-left: 20px"><em>Low cFT, even in the presence of normal TT, is associated with androgen deficiency-related symptoms. Normal cFT, despite low TT, is not associated with cognate symptoms; therefore, cFT levels should be assessed in men with suspected hypogonadal symptoms.</em></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/26909800/[/URL]</p><p></p><p></p><p>Contrary to popular belief, SHBG does not have much effect on free testosterone in ordinary circumstances. Free testosterone is driven almost entirely by the rate of testosterone production—or the dose rate in men on TRT. </p><p></p><p>What method are you using to get free testosterone? Some of your calculated values seem robust. For example, TT of 788 ng/dL and SHBG of 54 nMol/L -> cFT ~= 13 ng/dL. With testosterone normal one should look for other reasons for the problems. With hCG it's possible to have estradiol and/or prolactin higher than ideal. Enclomiphene is potentially the opposite, being too effective of an antagonist in places where we need the estrogenic activity.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 255740, member: 38109"] Call BS on him. [INDENT][I]Low FT level, even in the presence of normal TT, is associated with ED severity in young men.[/I][/INDENT] [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/30349000/[/URL] [INDENT][I]Low cFT, even in the presence of normal TT, is associated with androgen deficiency-related symptoms. Normal cFT, despite low TT, is not associated with cognate symptoms; therefore, cFT levels should be assessed in men with suspected hypogonadal symptoms.[/I][/INDENT] [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/26909800/[/URL] Contrary to popular belief, SHBG does not have much effect on free testosterone in ordinary circumstances. Free testosterone is driven almost entirely by the rate of testosterone production—or the dose rate in men on TRT. What method are you using to get free testosterone? Some of your calculated values seem robust. For example, TT of 788 ng/dL and SHBG of 54 nMol/L -> cFT ~= 13 ng/dL. With testosterone normal one should look for other reasons for the problems. With hCG it's possible to have estradiol and/or prolactin higher than ideal. Enclomiphene is potentially the opposite, being too effective of an antagonist in places where we need the estrogenic activity. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Need help with T-Cypionate - Vials (Single vs. multiple - What do you guys use?)
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