Need Help With AI Dose Since Doctor Can't Help

You sound very similar to me. Mine was at 60. Just started a .125mg twice weekly protocol. Hopefully it has the same impact as yours did.

Hope it works well for you. Mine had risen to 52 about 10 weeks ago and typically fluctuated between 40 and 50. Most would say I did not need an AI, and by the numbers I would agree....but my symptoms said otherwise! I dose T CYP 50mg every 3.5D, with 500iu HCG same schedule. I was very hesitant to start the AI, but now glad I did. Tested a couple of weeks ago and E2 came back 26.2, my second test since starting the AI. Feeling very good right now and it seems to have settled In that range.
 
Hope it works well for you. Mine had risen to 52 about 10 weeks ago and typically fluctuated between 40 and 50. Most would say I did not need an AI, and by the numbers I would agree....but my symptoms said otherwise! I dose T CYP 50mg every 3.5D, with 500iu HCG same schedule. I was very hesitant to start the AI, but now glad I did. Tested a couple of weeks ago and E2 came back 26.2, my second test since starting the AI. Feeling very good right now and it seems to have settled In that range.

My E2 was at 15 before I started TRT. Went to 19 after 5 weeks on 100mg test / 1500IU HCG once per week. Then I found out I had low SHBG and switched to 40mg test EOD and 500IU HCG twice per week. After 8 weeks on that protocol, my E2 rised to 60. I felt fantastic at about week 3 of the new protocol for about 5 days....Libido and ED both were outstanding. Then it went away. So based on that, I feel like my sweet spot for E2 is lower than where I'm at today and I hit that sweet spot for 5 days as my E2 was rising. I am starting a low dose AI to get it down to that sweet spot.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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