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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
NATESTO/Tlando
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<blockquote data-quote="madman" data-source="post: 265347" data-attributes="member: 13851"><p>You should vey well know I am well aware of the studies.</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/patient-satisfaction-after-switching-to-jatenzo-oral-tu.25999/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/oral-tu-offers-a-safe-and-effective-long-term-treatment-option-for-men-with-hypogonadism.26398/[/URL]</p><p></p><p><strong>Strengths and Limitations</strong></p><p></p><p><em>This study provides the first long-term data regarding the safety of a novel SEDDS formulation of oral TU. <strong>One potential limitation is that data in the current 2-year analysis were observational and not compared with a control or active-treatment group. However, this patient population was compared to a cohort treated with transdermal T in the initial 1-year randomized study. That analysis found similar efficacy and safety outcomes between the formulations.4</strong> <strong><u>Nonetheless, the comparative long-term safety of oral TU vs transdermal T gel and other T formulations would be strengthened by confirmatory studies</u>. </strong>In addition, while the number of patients followed for 2 years in this study was modest in size, it is sufficiently large to derive comfort that the observations regarding the safety of oral TU are accurate, and thus reassuring for medical practitioners who may prescribe oral TU for appropriate hypogonadal patients.</em></p><p><em></em></p><p><em>In addition, the PDQ was utilized to evaluate multiple parameters of sexual function, more appropriate for evaluating patients who are treated with testosterone therapy. <strong>We did not evaluate erectile dysfunction with the IIEF questionnaire in this study.</strong></em></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/oral-testosterone-versus-topical-testosterone-larger-decreases-in-hdl.25218/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/comparison-between-jatenzo%C2%AE-and-androgel%C2%AE-in-tt-ft-and-shbg-after-1yr-of-therapy.25215/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/linear-relationship-between-the-time-of-dosing-and-24-hr-cavg-of-tt-in-men-treated-with-jatenzo%C2%AE.25184/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/significant-decrease-in-shbg-with-the-use-of-oral-tu-jatenzo.25143/#post-221581[/URL]</p><p></p><p></p><p></p><p></p><p>Again I am not talking about the effectiveness when it comes to relief/improvement of low-T symptoms.</p><p></p><p>Again read over post # 6.</p><p></p><p></p><p><em><strong>Main advantage is Jatenzo will keep your T levels elevated longer over the 24 hr period let alone have more beneficial effect when it comes to body composition changes (muscle/fat loss).</strong></em></p><p><em><strong></strong></em></p><p><em><strong>Main downfall of Natesto let alone Jatenzo is you will not be able to keep T levels supra-physiological 24/7 steady-state due to the short acting half-life which is needed in order to reap the full anabolic potential of the hormone we all love TESTOSTERONE!</strong></em></p><p><em><strong></strong></em></p><p><em><strong>Injectables will always be king when it comes to increasing muscle/strength due to being able to attain high/absurdly high TT/FT levels 24/7 steady-state.</strong></em></p><p><em><strong></strong></em></p><p><em><strong>Other than being the cheapest method it is a given that you can attain high/absurdly high TT/FT levels 24/7 using injectable esterified T.</strong></em></p><p></p><p><strong><em>Most men would not waste their time with Natesto or any oral formulation (Andriol, Jatenzo, Tlando, Kyzatrex) of T due to the simple fact that you are going to miss out on the full anabolic benefits.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 265347, member: 13851"] You should vey well know I am well aware of the studies. [URL unfurl="true"]https://www.excelmale.com/forum/threads/patient-satisfaction-after-switching-to-jatenzo-oral-tu.25999/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/oral-tu-offers-a-safe-and-effective-long-term-treatment-option-for-men-with-hypogonadism.26398/[/URL] [B]Strengths and Limitations[/B] [I]This study provides the first long-term data regarding the safety of a novel SEDDS formulation of oral TU. [B]One potential limitation is that data in the current 2-year analysis were observational and not compared with a control or active-treatment group. However, this patient population was compared to a cohort treated with transdermal T in the initial 1-year randomized study. That analysis found similar efficacy and safety outcomes between the formulations.4[/B] [B][U]Nonetheless, the comparative long-term safety of oral TU vs transdermal T gel and other T formulations would be strengthened by confirmatory studies[/U]. [/B]In addition, while the number of patients followed for 2 years in this study was modest in size, it is sufficiently large to derive comfort that the observations regarding the safety of oral TU are accurate, and thus reassuring for medical practitioners who may prescribe oral TU for appropriate hypogonadal patients. In addition, the PDQ was utilized to evaluate multiple parameters of sexual function, more appropriate for evaluating patients who are treated with testosterone therapy. [B]We did not evaluate erectile dysfunction with the IIEF questionnaire in this study.[/B][/I] [URL unfurl="true"]https://www.excelmale.com/forum/threads/oral-testosterone-versus-topical-testosterone-larger-decreases-in-hdl.25218/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/comparison-between-jatenzo%C2%AE-and-androgel%C2%AE-in-tt-ft-and-shbg-after-1yr-of-therapy.25215/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/linear-relationship-between-the-time-of-dosing-and-24-hr-cavg-of-tt-in-men-treated-with-jatenzo%C2%AE.25184/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/significant-decrease-in-shbg-with-the-use-of-oral-tu-jatenzo.25143/#post-221581[/URL] Again I am not talking about the effectiveness when it comes to relief/improvement of low-T symptoms. Again read over post # 6. [I][B]Main advantage is Jatenzo will keep your T levels elevated longer over the 24 hr period let alone have more beneficial effect when it comes to body composition changes (muscle/fat loss). Main downfall of Natesto let alone Jatenzo is you will not be able to keep T levels supra-physiological 24/7 steady-state due to the short acting half-life which is needed in order to reap the full anabolic potential of the hormone we all love TESTOSTERONE! Injectables will always be king when it comes to increasing muscle/strength due to being able to attain high/absurdly high TT/FT levels 24/7 steady-state. Other than being the cheapest method it is a given that you can attain high/absurdly high TT/FT levels 24/7 using injectable esterified T.[/B][/I] [B][I]Most men would not waste their time with Natesto or any oral formulation (Andriol, Jatenzo, Tlando, Kyzatrex) of T due to the simple fact that you are going to miss out on the full anabolic benefits.[/I][/B] [/QUOTE]
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