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I am not talking about the effectiveness when it comes to relief/improvement of low-T symptoms.


Many men may fair well using oral T and would most likely feel better off overall than fast-acting Natesto.


Comes down to the individual.


I am speaking in terms of the anabolic properties of testosterone (muscle/strength/recovery).


Minimal gains in muscle/strength using Natesto let alone oral esterified T.


No comparison between the gains in muscle/strength that one would attain using the higher-end TRT dose of 200 mg T/week vs Natesto or any other formulation of oral TU.


Key here is achieving supra-physiological levels 24/7 steady state.


This could never be done with Natesto let alone oral T therapy!


Not a chance in hell!


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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