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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Dosage - How much T?
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<blockquote data-quote="Cataceous" data-source="post: 171879" data-attributes="member: 38109"><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837307/" target="_blank">This review article</a> notes that:</p><p></p><p style="margin-left: 20px"><em>Nandrolone binds to androgen receptors with a greater binding affinity than testosterone and with an increased anabolic, or myotrophic, activity rate (versus androgenic activity) (15). For example and to assist in comparison, the myotrophic:androgenic ratio can be used to compare testosterone (~1:1) to nandrolone (~11:1) (15) with regards to the ability to stimulate muscle growth compared to virilization.</em></p> <p style="margin-left: 20px"></p><p>Confirming the part about SHBG, Wikipedia cites a relative binding affinity for nandrolone that is 1/19 that of testosterone and 1/100 that of DHT.</p><p></p><p>What's not obvious to me is whether nandrolone can significantly affect free testosterone levels. Nandrolone does displace some testosterone from androgen receptors, but how do these numbers compare to the overall amount of free testosterone in circulation?</p></blockquote><p></p>
[QUOTE="Cataceous, post: 171879, member: 38109"] [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837307/']This review article[/URL] notes that: [INDENT][I]Nandrolone binds to androgen receptors with a greater binding affinity than testosterone and with an increased anabolic, or myotrophic, activity rate (versus androgenic activity) (15). For example and to assist in comparison, the myotrophic:androgenic ratio can be used to compare testosterone (~1:1) to nandrolone (~11:1) (15) with regards to the ability to stimulate muscle growth compared to virilization.[/I][/INDENT] [INDENT][/INDENT] Confirming the part about SHBG, Wikipedia cites a relative binding affinity for nandrolone that is 1/19 that of testosterone and 1/100 that of DHT. What's not obvious to me is whether nandrolone can significantly affect free testosterone levels. Nandrolone does displace some testosterone from androgen receptors, but how do these numbers compare to the overall amount of free testosterone in circulation? [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Dosage - How much T?
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