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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My journey so far with low testosterone.
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<blockquote data-quote="dnfuss" data-source="post: 97123" data-attributes="member: 15487"><p>CSI007, While metformin half-life is not as long as that of testosterone cypionate, it is not fast-acting in all of its effects. Any time you make any change, such as going from regular metformin to ER, you need to give it at least three weeks to see how things may settle out, maybe longer. Remember, you're interfering with hepatic glucose production and glucose uptake at the cellular level. These are hormonal processes that are complicated and interactive. Patience and careful observation are required. Perhaps you will conclude after giving it some time that you indeed see better results from regular metformin than from the ER version. But as with TRT, rapid and/or multiple protocol changes based on subjective feelings or short-term lab values are to be avoided. Also note that many patients feel that they react quite differently to one brand of generic metformin versus another, and find that switching generic brands can sometimes bring improvement in glucose regulation and side effects.</p></blockquote><p></p>
[QUOTE="dnfuss, post: 97123, member: 15487"] CSI007, While metformin half-life is not as long as that of testosterone cypionate, it is not fast-acting in all of its effects. Any time you make any change, such as going from regular metformin to ER, you need to give it at least three weeks to see how things may settle out, maybe longer. Remember, you're interfering with hepatic glucose production and glucose uptake at the cellular level. These are hormonal processes that are complicated and interactive. Patience and careful observation are required. Perhaps you will conclude after giving it some time that you indeed see better results from regular metformin than from the ER version. But as with TRT, rapid and/or multiple protocol changes based on subjective feelings or short-term lab values are to be avoided. Also note that many patients feel that they react quite differently to one brand of generic metformin versus another, and find that switching generic brands can sometimes bring improvement in glucose regulation and side effects. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My journey so far with low testosterone.
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