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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My journey so far with low testosterone.
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<blockquote data-quote="dnfuss" data-source="post: 96291" data-attributes="member: 15487"><p>That is what the ADA says. They also say that any A1c below 5.7% is acceptable (that's an average glucose level of 117 mg/dl or more). But thorough population studies demonstrate that those who are truly euglycemic and euinsulinemic (completely normal and robust blood sugar regulation throughout life) have fasting glucose levels of 70-92 mg/dl, A1c in the high-4% to low-5% range, and almost never go above 120 mg/dl after meals -- no matter what they eat (and even after drinking 75 or 100 grams of glucose during an oral glucose tolerance test).</p><p></p><p></p><p></p><p>Don't believe it did, but in one sense the amount of carbs consumed is irrelevant. That is, what counts is the serum glucose level. Complications and damage aren't caused by carbs; they're caused by high blood sugars. If you have truly normal blood sugars you can eat all the carbs in the world and you'll never get diabetic complications and damage because you never have high fasting blood sugars or high post-meal spikes. Conversely, if you are a full-blown Type 1 diabetic (few or no remaining beta cells), you can eat a nearly zero-carb diet, exercise religiously and be thin as a rail, but you'll still sustain diabetic complications and damage if you don't control your blood sugar carefully with exogenous insulin.</p><p></p><p></p><p></p><p>A longer study is actually more meaningful because weak associations tend to disappear over time. When you're talking about large epidemiological studies and control for all other variables, a difference in all-cause mortality over 33 years of 76% between the group with the lowest (although still high) post-meal blood sugars and the highest is quite statistically significant (i.e., extremely unlikely that it was due to chance). It's true that this isn't a randomized, controlled trial (you couldn't do one of those ethically), but it is good evidence for the proposition that high post-meal blood glucose spikes (especially at one hour) correlate directly with morbidity and mortality.</p><p></p><p> </p><p></p><p>Some patients with blood sugar issues are able to modify their diets and exercise and achieve normal blood sugars. I hope you are one of them. I found that my blood sugars improved with diet and exercise but I had to add Metformin to achieve normal blood sugars and that if I go off Metformin my blood sugars will rise.</p><p></p><p></p><p></p><p> Not sure what is the healthy range of blood glucose that is being used for reference, but for diabetics who are type 1 or full-blown type 2 (fasting glucose above 125 mg/dl, post-meals above 180 mg/dl, A1c above 6.0%), achieving and maintaining truly normal blood sugars (as described above) without drugs is uncommon.</p><p></p><p>I wish you good luck.</p></blockquote><p></p>
[QUOTE="dnfuss, post: 96291, member: 15487"] That is what the ADA says. They also say that any A1c below 5.7% is acceptable (that's an average glucose level of 117 mg/dl or more). But thorough population studies demonstrate that those who are truly euglycemic and euinsulinemic (completely normal and robust blood sugar regulation throughout life) have fasting glucose levels of 70-92 mg/dl, A1c in the high-4% to low-5% range, and almost never go above 120 mg/dl after meals -- no matter what they eat (and even after drinking 75 or 100 grams of glucose during an oral glucose tolerance test). Don't believe it did, but in one sense the amount of carbs consumed is irrelevant. That is, what counts is the serum glucose level. Complications and damage aren't caused by carbs; they're caused by high blood sugars. If you have truly normal blood sugars you can eat all the carbs in the world and you'll never get diabetic complications and damage because you never have high fasting blood sugars or high post-meal spikes. Conversely, if you are a full-blown Type 1 diabetic (few or no remaining beta cells), you can eat a nearly zero-carb diet, exercise religiously and be thin as a rail, but you'll still sustain diabetic complications and damage if you don't control your blood sugar carefully with exogenous insulin. A longer study is actually more meaningful because weak associations tend to disappear over time. When you're talking about large epidemiological studies and control for all other variables, a difference in all-cause mortality over 33 years of 76% between the group with the lowest (although still high) post-meal blood sugars and the highest is quite statistically significant (i.e., extremely unlikely that it was due to chance). It's true that this isn't a randomized, controlled trial (you couldn't do one of those ethically), but it is good evidence for the proposition that high post-meal blood glucose spikes (especially at one hour) correlate directly with morbidity and mortality. Some patients with blood sugar issues are able to modify their diets and exercise and achieve normal blood sugars. I hope you are one of them. I found that my blood sugars improved with diet and exercise but I had to add Metformin to achieve normal blood sugars and that if I go off Metformin my blood sugars will rise. Not sure what is the healthy range of blood glucose that is being used for reference, but for diabetics who are type 1 or full-blown type 2 (fasting glucose above 125 mg/dl, post-meals above 180 mg/dl, A1c above 6.0%), achieving and maintaining truly normal blood sugars (as described above) without drugs is uncommon. I wish you good luck. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My journey so far with low testosterone.
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