My Clomid Journal

m1johnson

New Member
I started on clomid about a week ago. I'll try to remember to keep this journal updated to give people some insight. I am working with Dr. Saya and the Defy team as doctors locally consider all my levels normal despite the symptoms.

23 year old male, no steroid use, have had panic attacks/anxiety since i was 16 or so which runs in my family.

25mg Clomid daily
DHEA/Pregnenolone 15mg/25mg daily

Labs -
Thyroid Panel With TSH
TSH 4.220 (0.450-4.500 uIU/mL)
Thyroxine (T4) 4.8 (4.5-12.0 ug/dL)
T3 Uptake 37 (24-39 %)
Free Thyroxine Index 1.8 (1.2-4.9)


Testosterone, Free/Tot Equilib
Testosterone, Serum 481 (348-1197 ng/dL)
Testosterone,Free 11.69 (5.00-21.00 ng/dL)
% Free Testosterone 2.43 (1.50-4.20 %)

DHEA-Sulfate 280.0 ug/dL (164.3 - 530.5)
Luteinizing Hormone(LH) 3.5 mIU/mL (1.7 - 8.6)


Recent thyroid labs -

Thyroxine (T4) Free, Direct, S
T4,Free(Direct) 1.32 ng/dL (0.82 - 1.77)
TSH 5.470 High uIU/mL (0.450 - 4.500)
Reverse T3, Serum 13.2 ng/dL (9.2 - 24.1)
Thyroglobulin Antibody 0.0 IU/mL (0.0 - 0.9)
Thyroglobulin Antibody measured by Beckman Coulter Methodology
Thyroid Peroxidase (TPO) Ab 7 IU/mL (0 - 34)
Triiodothyronine,Free,Serum 2.7 pg/mL (2.0 - 4.4)



I saw an endocrinologist locally who went over my thyroid lab work. I wanted to get a 2nd opinion as Defy and my primary doctor were concerned with the levels. The endo ordered some more labs but said with these current levels he sees no need to treat it. He specializes in thyroid disorders. I have a consultation with a Defy nurse this week so we'll see what they say.

The main symptoms i'd like to fix are fatigue, irritability, weight gain/less strength and overall well being. I don't feel the same after my workouts like I did 3 years ago. So far after a week I can't say I notice much which is to be expected based on what i've been told and read. Maybe a slight increase in energy levels. I felt great during my Tuesday workout but on Thursday felt like crap.

I am not sure what the plan is if clomid ends up working. Maybe long term use of clomid or something else?
 
Last edited:
Welcome to Excelmale. Your post is rather incomplete. You are on Clomid? If so, can you provide us with protocol details? You mentioned something about not noticing any changes in a week. That isn't a lot of time; androgen replacement requires patience. Is your protocol prescribed by the team at Defy, or locally? Again, I found it a bit ambiguous. Finally, was your SHBG and estradiol measured?
 
Welcome to Excelmale. Your post is rather incomplete. You are on Clomid? If so, can you provide us with protocol details? You mentioned something about not noticing any changes in a week. That isn't a lot of time; androgen replacement requires patience. Is your protocol prescribed by the team at Defy, or locally? Again, I found it a bit ambiguous. Finally, was your SHBG and estradiol measured?

I completely forgot to add the dosages for the medications. I updated the OP. It was prescribed by Defy. I understand it will take awhile and i'm willing to be patient hopefully my post didn't come across as me being impatient. From my understanding it will be 3-4 more weeks before anything noticeable occurs.
 
This is bloodwork from a week ago. Been on clomid now for roughly a month.

fa213f1afabd4dedaaaaeb415cf17a31.png




c8a9421f419541c8869fbc1497f59da1.png


I felt better 2 weeks ago than I feel now. Brain fog and my head just feels spacey. Tough to describe. Feeling tired especially in the mornings. Less morning erections. Probably the high estradiol levels but i'll see what Defy recommends.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
0
Guests online
407
Total visitors
407

Latest posts

Back
Top