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Message: <blockquote data-quote="CoastWatcher" data-source="post: 22769" data-attributes="member: 2624">Low SHBG is a marker, it can occur in metabolic syndrome/diabetes, and testing can determine if a person is dealing with issues such as insulin resistance, diabetes, metabolic syndrome. The majority of men with low SHBG do not have these issues to contend with. Dealing with low SHBG is just another factor that some men have to deal with when implementing a TRT protocol. Usually it is something that can be dealt with via more frequent, smaller injections of testosterone. There are instances where it becomes a real obstacle to successful TRT management. There are excellent threads here on the Forum that can be accessed via searching. They will provide you with a lot of good reading.</blockquote>

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