madman
Super Moderator
Dr. Peter Wilson
I am going to give you some pearls from recent talks.
1:28-2:19
* Shehzad Basaria from Harvard who's on the TRAVERSE Trial. He said one of the biggest mistakes were making is assuming free testosterone is correct. Thats important and I think we in endocrinology and urology we should really make sure that were getting good accurate. He does not think free testosterone is done very well except you send it out to reference labs. So that means you have to use the SHBG formula and most of us don't have time to do that but we should probably start leaning on our local labs to do the Equilibrium Dialysis that's the key word ED, Equilibrium Dialysis measurement if you are going to be treating a lot of them and your going to be managing androgen levels, that's number one
I am going to give you some pearls from recent talks.
1:28-2:19
* Shehzad Basaria from Harvard who's on the TRAVERSE Trial. He said one of the biggest mistakes were making is assuming free testosterone is correct. Thats important and I think we in endocrinology and urology we should really make sure that were getting good accurate. He does not think free testosterone is done very well except you send it out to reference labs. So that means you have to use the SHBG formula and most of us don't have time to do that but we should probably start leaning on our local labs to do the Equilibrium Dialysis that's the key word ED, Equilibrium Dialysis measurement if you are going to be treating a lot of them and your going to be managing androgen levels, that's number one
Male Reproduction and Aging (2023)
Maria Gabriela Figueiredo, MD, Thiago Gagliano-Jucá, MD, PhD, Shehzad Basaria, MD
INTRODUCTION
Aging of humans is associated with functional alterations at all levels of the reproductive axis and affects both steroidogenic and spermatogenic compartments. Unlike female reproductive aging (menopause) or organic androgen deficiency in men (due to diseases of the hypothalamus, pituitary, or testes), male reproductive aging does not result in absolute cessation of testosterone production or spermatogenesis (Table 1). In fact...
Maria Gabriela Figueiredo, MD, Thiago Gagliano-Jucá, MD, PhD, Shehzad Basaria, MD
INTRODUCTION
Aging of humans is associated with functional alterations at all levels of the reproductive axis and affects both steroidogenic and spermatogenic compartments. Unlike female reproductive aging (menopause) or organic androgen deficiency in men (due to diseases of the hypothalamus, pituitary, or testes), male reproductive aging does not result in absolute cessation of testosterone production or spermatogenesis (Table 1). In fact...
- madman
- testosterone; loh; aging; trt
- Replies: 6
- Forum: Testosterone and Men's Health Articles
Accurate measurement of total and free testosterone levels for the diagnosis of androgen disorders (7/2022)
Ezgi Caliskan Guzelce, MD, Clinical/ Research Fellow, Francesca Galbiati, MD, Fellow, Anna L. Goldman, MD, Assistant Professor of Medicine, Arijeet K. Gattu, MD, Fellow, Shehzad Basaria, MD, Professor of Medicine, Shalender Bhasin, MB, BS, Professor of Medicine, Director
ABSTRACT
The circulating concentrations of total and free testosterone vary substantially in people over time due to biological factors as well as due to measurement variation. Accurate...
Ezgi Caliskan Guzelce, MD, Clinical/ Research Fellow, Francesca Galbiati, MD, Fellow, Anna L. Goldman, MD, Assistant Professor of Medicine, Arijeet K. Gattu, MD, Fellow, Shehzad Basaria, MD, Professor of Medicine, Shalender Bhasin, MB, BS, Professor of Medicine, Director
ABSTRACT
The circulating concentrations of total and free testosterone vary substantially in people over time due to biological factors as well as due to measurement variation. Accurate...
- madman
- hypogonadism; testosterone; free testosterone
- Replies: 7
- Forum: Testosterone and Men's Health Articles
FIGURE 1 Direct and indirect mechanisms by which opioids cause hypogonadism. +, stimulation; -, inhibition; FSH, follicle-stimulating hormone; GnRH, gonadotropin-releasing hormone; LH, luteinizing hormone; PRL, prolactin; T, testosterone.
Hussein Kafel, Milena Braga-Basaria, Shehzad Basaria
Abstract
Background
Opioid analgesics are frequently prescribed for the treatment of chronic pain and are a common cause of male...
Opioid-induced androgen deficiency in men. Prevalence, pathophysiology, and efficacy of testosterone therapy (2025)Hussein Kafel, Milena Braga-Basaria, Shehzad Basaria
Abstract
Background
Opioid analgesics are frequently prescribed for the treatment of chronic pain and are a common cause of male...
- madman
- hypogonadism; opioids; testosterone; ed; screening
- Replies: 8
- Forum: Health & Wellness
Speakers:
Dr. Ali Khalil
Consultant Diabetologist & Endocrinologist
Imperial College London Diabetes Centre
Prof. Richard Quinton
MB BChir MA MD from Cambridge University
Consultant Endocrinologist, Newcastle
upon Tyne Hospitals & Senior Lecturer,
Translational & Clinical Research Institute,
Newcastle University
Prof. Shehzad Basaria
Professor of Medicine
Harvard Medical School
Associate Director, Section on Men's Health,
Aging & Metabolism
Brigham & Women's Hospital
...
Dr. Ali Khalil
Consultant Diabetologist & Endocrinologist
Imperial College London Diabetes Centre
Prof. Richard Quinton
MB BChir MA MD from Cambridge University
Consultant Endocrinologist, Newcastle
upon Tyne Hospitals & Senior Lecturer,
Translational & Clinical Research Institute,
Newcastle University
Prof. Shehzad Basaria
Professor of Medicine
Harvard Medical School
Associate Director, Section on Men's Health,
Aging & Metabolism
Brigham & Women's Hospital
- madman
- hypogonadism; testosterone; men's health
- Replies: 17
- Forum: Testosterone and Men's Health Articles