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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Men with low T report similar satisfaction on Clomid as they do on testosterone replacement
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<blockquote data-quote="Nelson Vergel" data-source="post: 8452" data-attributes="member: 3"><p>I do not know if I believe this.</p><p></p><p>(From the American Urology Association Conf- May 2-14- Orlando)</p><p></p><p>MP48-06: <strong>HYPOGONADAL MEN TAKING CLOMIPHENE CITRATE REPORT SIMILAR SATISFACTION COMPARED TO MEN ON TESTOSTREONE REPLACEMENT THERAPY</strong> </p><p>Ranjith Ramasamy*, Jason Scovell, Jason Kovac, James Dupree, Gavin Langille, Dolores Lamb, Larry Lipshultz, Houston, TX<strong></strong></p><p><strong></strong></p><p><strong>Abstract: MP48-06</strong> </p><p><strong>Introduction and Objectives</strong> </p><p>The efficacy of oral clomiphene citrate (CC) in the treatment of male hypogonadism has been reported. We compared satisfaction and treatment efficacy in men with symptomatic hypogonadism taking CC, testosterone gel (T gel), and testosterone injections (T injections). </p><p></p><p><strong>Methods</strong> </p><p>Men receiving CC or T gel or T injections for symptomatic hypogonadism (total testosterone < 300 ng/dl) were asked to report satisfaction with their current treatment regimen with ADAM and qADAM scores. Serum testosterone levels were collected on the same day that men filled out the ADAM questionnaire. Treatment efficacy was evaluated using pre- and post-treatment serum testosterone, and satisfaction was assessed using androgen deficiency in aging male (ADAM) and quantitative ADAM (qADAM) questionnaire scores </p><p></p><p><strong>Results</strong> </p><p>The charts of 451 men on testosterone supplementation (51 on CC, 265 on T injections, and 135 on T gel) were reviewed. The mean serum total T levels in men on CC (525 ng/dL) was lower (p<0.01) than men taking T injections (1015 ng/dL), but similar to serum total T in men on gels (453.3 ng/dL, p=0.07). Post-treatment testosterone levels were higher in men taking CC, T injections and T gels compared to pre-treatment levels (227 ng/dL, 221 ng/dL, 211 ng/dL p<0.01) Despite differences in serum T, men on CC, T injection, and T gel reported similar satisfaction levels. Both the ADAM scores (2.37, 2.81, and 3.17) and quantitative ADAM scores (37.2, 36.8, and 35.6) for the men on different testosterone supplementation regimens were similar. Men taking CC were younger (38.5y) than men taking T injections (46.8y) or T gels (59.4, p< 0.01). </p><p></p><p><strong>Conclusions</strong> </p><p>Testosterone supplementation regimens including CC, T gels and T injections are efficacious in improving serum total testosterone levels. However, men taking clomiphene citrate or testosterone gels report similar satisfaction levels compared to men taking testosterone injections despite lower serum total testosterone levels.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 8452, member: 3"] I do not know if I believe this. (From the American Urology Association Conf- May 2-14- Orlando) MP48-06: [B]HYPOGONADAL MEN TAKING CLOMIPHENE CITRATE REPORT SIMILAR SATISFACTION COMPARED TO MEN ON TESTOSTREONE REPLACEMENT THERAPY[/B] Ranjith Ramasamy*, Jason Scovell, Jason Kovac, James Dupree, Gavin Langille, Dolores Lamb, Larry Lipshultz, Houston, TX[B] Abstract: MP48-06[/B] [B]Introduction and Objectives[/B] The efficacy of oral clomiphene citrate (CC) in the treatment of male hypogonadism has been reported. We compared satisfaction and treatment efficacy in men with symptomatic hypogonadism taking CC, testosterone gel (T gel), and testosterone injections (T injections). [B]Methods[/B] Men receiving CC or T gel or T injections for symptomatic hypogonadism (total testosterone < 300 ng/dl) were asked to report satisfaction with their current treatment regimen with ADAM and qADAM scores. Serum testosterone levels were collected on the same day that men filled out the ADAM questionnaire. Treatment efficacy was evaluated using pre- and post-treatment serum testosterone, and satisfaction was assessed using androgen deficiency in aging male (ADAM) and quantitative ADAM (qADAM) questionnaire scores [B]Results[/B] The charts of 451 men on testosterone supplementation (51 on CC, 265 on T injections, and 135 on T gel) were reviewed. The mean serum total T levels in men on CC (525 ng/dL) was lower (p<0.01) than men taking T injections (1015 ng/dL), but similar to serum total T in men on gels (453.3 ng/dL, p=0.07). Post-treatment testosterone levels were higher in men taking CC, T injections and T gels compared to pre-treatment levels (227 ng/dL, 221 ng/dL, 211 ng/dL p<0.01) Despite differences in serum T, men on CC, T injection, and T gel reported similar satisfaction levels. Both the ADAM scores (2.37, 2.81, and 3.17) and quantitative ADAM scores (37.2, 36.8, and 35.6) for the men on different testosterone supplementation regimens were similar. Men taking CC were younger (38.5y) than men taking T injections (46.8y) or T gels (59.4, p< 0.01). [B]Conclusions[/B] Testosterone supplementation regimens including CC, T gels and T injections are efficacious in improving serum total testosterone levels. However, men taking clomiphene citrate or testosterone gels report similar satisfaction levels compared to men taking testosterone injections despite lower serum total testosterone levels. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Men with low T report similar satisfaction on Clomid as they do on testosterone replacement
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