ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Nutrition and Supplements
Melatonin supplements before evening meal - yes or no?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="seppuku" data-source="post: 271044" data-attributes="member: 2030"><p>OK, well this study completely contradicts the one above and says that eating with raised melatonin levels can lead to type 2 diabetes.</p><p></p><p>A quote from the study -</p><p></p><p>"In this Timing Model, low melatonin (during eating) supports high glucose tolerance, while high melatonin (during fasting) would facilitate β-cell recovery. Therefore, the abnormal state of high melatonin concurrent with food intake, as seen in nocturnally feeding populations, shift-workers or users of exogenous melatonin, may result in dysregulation of glucose metabolism leading to increased risk of T2D. Furthermore, abnormally low melatonin levels or decreased melatonin receptor signaling during the night (as might occur in carriers of rare loss-of-function mutations in <em>MTNR1B</em>), may limit β-cell recovery, and chronically raise T2D risk."</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349733/[/URL]</p></blockquote><p></p>
[QUOTE="seppuku, post: 271044, member: 2030"] OK, well this study completely contradicts the one above and says that eating with raised melatonin levels can lead to type 2 diabetes. A quote from the study - "In this Timing Model, low melatonin (during eating) supports high glucose tolerance, while high melatonin (during fasting) would facilitate β-cell recovery. Therefore, the abnormal state of high melatonin concurrent with food intake, as seen in nocturnally feeding populations, shift-workers or users of exogenous melatonin, may result in dysregulation of glucose metabolism leading to increased risk of T2D. Furthermore, abnormally low melatonin levels or decreased melatonin receptor signaling during the night (as might occur in carriers of rare loss-of-function mutations in [I]MTNR1B[/I]), may limit β-cell recovery, and chronically raise T2D risk." [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349733/[/URL] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Nutrition and Supplements
Melatonin supplements before evening meal - yes or no?
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top