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Hi, some questions regarding the new Oral Native Testosterone + Enclomiphene combo.

If someone can help me out with some wisdom (e.g. [USER=38632]@docc[/USER]), awesome!

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Baseline / Context:

• Healthy male, athletic, non obese, mid 30s
• Total cholesterol: ~100 (on low-dose statin + ezetimibe)
• Baseline:
• Total T: ~500 ng/dlLH: 4.9 IU/L, SHBG: 42 nmol/l
  • Total T: ~500 ng/dl
  • LH: 4.9
  • Estradiol: 20,2 pg/ml
  • SHBG: 42 nmol/l
• After 3 months of enclomiphene only (6 mg every 3 days):
  • Total T: ~850 ng/dl
  • LH: ~13 (reference range: IU/L 1,7 - 8,6 IU/L)
  • Estradiol: 43.6 pg/ml (reference range: 11,3 - 43,2 pg/ml)
  • SHBG: 80.5 nmol/l (reference range: 18,3 - 54,1 nmol/l)

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Questions:

• What could be a good oral T dose added to enclo — 400 mg or 600 mg?
• What total T levels are realistic from that setup?
• Does 2x dosing help anything?
• If dosing 2x/day is beneficial:
  • How many hours later would you take the second dose?
  • Equal split or e.g. 70/30?
  • Does 2x dosing cause suppression? Or increase E2 conversion?
• I heard cholesterol below 130 might impair steroid production —
  would it make sense to add pregnenolone because of this?

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Thanks very much!