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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)
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<blockquote data-quote="madman" data-source="post: 277308" data-attributes="member: 13851"><p>Mesterolone sensible doses would have the least impact.</p><p></p><p>Other than Natesto all forms of exogenous T let alone AAS will have a strong impact on suppression of endogenous T/hpta.</p><p></p><p>HRT doses of T let alone the doses used when abusing T/AAS for the sole purpose of muscle/strength gains.</p><p></p><p></p><p></p><p></p><p><strong>Side Effects (Testosterone Suppression):</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>Proviron (mesterolone)</strong></p><p><strong></strong></p><p><strong><em>Mesterolone has a very weak suppressive effect on gonadotropins and serum testosterone. Studies show that when given in moderate doses (150 mg per day or less), significant suppression of testosterone levels does not occur.574 <u>In studies with higher doses (300 mg per day and above), the agent strongly suppressed serum testosterone</u>.575</em></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>Anavar (oxandrolone)</strong></p><p><strong></strong></p><p><strong><em>All anabolic/androgenic steroids when taken in <u>doses sufficient to promote muscle gain are expected to suppress endogenous testosterone production</u>. <u>Oxandrolone is no exception</u>.</em></strong><em><strong> In the above-cited study on HIV+ males, twelve weeks of 20 mg or 40 mg per day caused an approximate 45% reduction in serum testosterone levels. The group taking 80 mg noticed a 66% decrease in testosterone. Similar trends of decrease were noticed in LH production, with the 20 mg and 40 mg doses causing a 25-30% reduction, and the 80 mg group noticing a decline of more than 50%. Additionally,studies on boys with constitutionally delayed puberty have demonstrated significant suppression of endogenous LH and testosterone with as little as 2.5 mg per day.</strong>410 Without the intervention of testosterone stimulating substances,testosterone levels should return to normal within 1-4 months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse,necessitating medical intervention.</em></p><p></p><p></p><p></p><p></p><p><strong>Halotestin (fluoxymesterone)</strong></p><p></p><p><em><strong>Studies administering 10 mg, 20 mg, or 30 mg off fluoxymesterone to nine healthy male subjects for up to 12 weeks have demonstrated the <u>strong suppression of endogenous testosterone levels, with inconsistent effects on gonadotropin levels</u>.</strong> <strong>Although not fully understood,fluoxymesterone is proposed to have a <u>direct suppressive effect on testicular steroidogenesis that is not mediated by the suppression gonadotropins</u>.514</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 277308, member: 13851"] Mesterolone sensible doses would have the least impact. Other than Natesto all forms of exogenous T let alone AAS will have a strong impact on suppression of endogenous T/hpta. HRT doses of T let alone the doses used when abusing T/AAS for the sole purpose of muscle/strength gains. [B]Side Effects (Testosterone Suppression): Proviron (mesterolone) [I]Mesterolone has a very weak suppressive effect on gonadotropins and serum testosterone. Studies show that when given in moderate doses (150 mg per day or less), significant suppression of testosterone levels does not occur.574 [U]In studies with higher doses (300 mg per day and above), the agent strongly suppressed serum testosterone[/U].575[/I] Anavar (oxandrolone) [I]All anabolic/androgenic steroids when taken in [U]doses sufficient to promote muscle gain are expected to suppress endogenous testosterone production[/U]. [U]Oxandrolone is no exception[/U].[/I][/B][I][B] In the above-cited study on HIV+ males, twelve weeks of 20 mg or 40 mg per day caused an approximate 45% reduction in serum testosterone levels. The group taking 80 mg noticed a 66% decrease in testosterone. Similar trends of decrease were noticed in LH production, with the 20 mg and 40 mg doses causing a 25-30% reduction, and the 80 mg group noticing a decline of more than 50%. Additionally,studies on boys with constitutionally delayed puberty have demonstrated significant suppression of endogenous LH and testosterone with as little as 2.5 mg per day.[/B]410 Without the intervention of testosterone stimulating substances,testosterone levels should return to normal within 1-4 months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse,necessitating medical intervention.[/I] [B]Halotestin (fluoxymesterone)[/B] [I][B]Studies administering 10 mg, 20 mg, or 30 mg off fluoxymesterone to nine healthy male subjects for up to 12 weeks have demonstrated the [U]strong suppression of endogenous testosterone levels, with inconsistent effects on gonadotropin levels[/U].[/B] [B]Although not fully understood,fluoxymesterone is proposed to have a [U]direct suppressive effect on testicular steroidogenesis that is not mediated by the suppression gonadotropins[/U].514[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)
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