Marius Pharmaceuticals Leads Effort to Redefine Women’s Health Through Testosterone Research

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* The newly formed all-female advisory board will provide clinical expertise, advocacy, and strategic guidance as Marius broadens its research and development in female hormone health.





All-female advisory board to guide Marius in addressing the unmet need for safe, effective testosterone therapies for women


Raleigh, N.C., (Nov. 4th, 2025) – Marius Pharmaceuticals, Inc., today announced the formation of an all-female advisory board to advance the company’s efforts in addressing the significant unmet need of testosterone deficiency in women.


While testosterone is widely recognized as a critical hormone for men, emerging research also highlights its vital role in women’s health, influencing energy, mood, muscle mass, metabolism, sexual health, and overall quality of life. Testosterone levels naturally decline in women with age, and this decrease becomes more pronounced during and after menopause, often contributing to symptoms that affect quality of life. Despite its importance, there are currently no FDA-approved testosterone therapies for women, leaving a significant gap in treatment options.

“At Marius, we are committed to advancing the scientific understanding of testosterone’s role in women’s health,” said Shalin Shah, CEO of Marius Pharmaceuticals. “This advisory board brings together some of the most accomplished experts in the field to help shape research priorities, foster clinical progress, and ultimately improve quality of life for women.”



Formation Of The Women’s Advisory Board


The newly formed all-female advisory board will provide clinical expertise, advocacy, and strategic guidance as Marius broadens its research and development in female hormone health. With the support of this esteemed group of leaders, Marius is establishing a dedicated research program focused on advancing safe and effective testosterone therapies for women.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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