Lp(a) [Lipoprotein(a)] - the hidden killer lipid marker

[style=font-family: Times New Roman;]As we learn more about how elevated levels of Lp(a) can potentially kill us before anyone can determine the cause, it is imperative that everyone get this lipid marker tested frequently, especially those on any type of HRT regimen. It is entirely possible that one of the leading culprits behind the upsurge of recent untimely deaths we've been seeing pop up left and right in the sports and bodybuilding community, in which "enhanced" athletes are pushing beyond human limits, could very well be unchecked elevated Lp(a) levels.[/style]
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Standard lipid panels are pretty much worthless for many reasons, one being that Lp(a) levels are never included. Thus, millions go unchecked that potentially could have avoided that MI (heart attack) or TIA (stroke), etc. had they known they were at risk.[/style]

[style=font-family: Times New Roman;]Only advanced lipid panels (i.e. Quest's Cardio IQ® Advanced Lipid Panel and Inflammation Panel) include Lp(a). Alternatively, you can test for it individually. I would also urge everyone 35+ to have a calcium score test done (EBCT or CCTA) to determine the levels of arterial plaque, as elevated Lp(a) can promote calcification
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I have been tracking my Lp(a) for the last several years. My last level was 118 which is considered moderate risk. However, back in 2012, I suffered from two episodes of idiopathic thrombophilia (blood clots of unknown origin) in both legs. I have been on a low-dose anticoagulant (blood thinner) prophylaxis since. As Lp(a) is thrombogenic (clot-producing) in nature, I was already at risk without knowing I had slightly elevated Lp(a), as all genetic thrombosis and other routine (i.e. RBC, HGB, HCT, E2) blood markers were normal. Neither exercise, diet or supplements have any impact, as one's Lp(a) are genetically-determined from birth.[/style]
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For those who've had the 23andMe.com test done early on, you have access to your raw data which includes the genetic markers that can help determine your predisposition for elevated levels of this marker. If interested, PM me, as I have done some research and have the actual genetic data (SNPs) that can help you see if you're at risk in addition to blood work.[/style]

[style=font-family: arial;]There is now an excellent Lp(a) foundation that is in place to help answer questions and educate those that are unfamiliar. It is also important to have all family members tested if your levels are elevated.[/style]
[style=color: #0433ff;]Click here: Lipoprotein(a) Foundation[/style]
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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