Low T Levels Associated with Blood Markers for CV

[Jinzang]

Over ten thousand blood sample results were examined and 9 out of 10 blood markers for cardiovascular disease were higher in in men with low testosterone.

The median age of the cohort was 58 years (interquartile range = 48–68), and the median plasma T level was 420 ng/dL (interquartile range = 304–565); T levels did not vary with patient age. An inverse relation between plasma T levels and CV risk was observed for 9 of 10 CV markers: cTnI, ET-1, IL-6, TNF-α, NTproBNP, HDL cholesterol, hs-CRP, HbA[SUB]1c[/SUB], and leptin. Even after adjusting for age, body mass index, HbA[SUB]1c[/SUB], hs-CRP, and HDL cholesterol levels, the CV markers IL-6, ET-1, NTproBNP, and leptin were significantly associated with a T level lower than 250 ng/dL.