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Some of us with low SHBG don't really clear T that much faster than normal even though that is always the expectation. I know that in my case I do not, as I was injecting E3.5 days for my first two years and there was never a pronounced difference between peak and valley.

My thyroid has always been fine as well but we have tried small doses of combined T3 & T4 to see if it made any difference and it has not. I think I will quite taking it after my next consult as it is just a waste of money for me.

Pellet therapy has a big problem with the fact that Docs are typically only allowed to inject them every 12 weeks, yet most guys on them drop to a "Low T" level after week 8 (plus or minus - it varies obviously with dosing and with each person being different) and then they are stuck with no recourse until week 12.