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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low SHBG Guys
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<blockquote data-quote="Cataceous" data-source="post: 158468" data-attributes="member: 38109"><p>I'd consider SHBG of 18-20 nMol/L to be just borderline-low.</p><p></p><p>It's a misconception to think that low SHBG causes testosterone to be used up more quickly when on TRT. The rate of use is essentially controlled by the rate of absorption. One way to think of it is that the testosterone injections control the level of free testosterone, and the combination of free testosterone and SHBG determines where total testosterone ends up.</p><p></p><p>If conventional wisdom is correct—about more frequent injections being better for low-SHBG guys—then the likely reduction of peak estradiol may well be one of the reasons why. The idea is somewhat supported in theory by the decrease in the ratio of free testosterone to free estradiol as SHBG goes lower.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 158468, member: 38109"] I'd consider SHBG of 18-20 nMol/L to be just borderline-low. It's a misconception to think that low SHBG causes testosterone to be used up more quickly when on TRT. The rate of use is essentially controlled by the rate of absorption. One way to think of it is that the testosterone injections control the level of free testosterone, and the combination of free testosterone and SHBG determines where total testosterone ends up. If conventional wisdom is correct—about more frequent injections being better for low-SHBG guys—then the likely reduction of peak estradiol may well be one of the reasons why. The idea is somewhat supported in theory by the decrease in the ratio of free testosterone to free estradiol as SHBG goes lower. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Low SHBG Guys
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