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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Libido and E2
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<blockquote data-quote="Cataceous" data-source="post: 152390" data-attributes="member: 38109"><p>It is true in an absolute sense, as far as averages go. It's you who may be the exception.</p><p></p><p>"Oral but not transdermal E2 increased SHBG concentrations by 67-171% in the control group..."[<a href="https://www.ncbi.nlm.nih.gov/pubmed/15784702" target="_blank">1</a>]</p><p></p><p>"<a href="https://en.wikipedia.org/wiki/Oral_contraceptive" target="_blank">Oral contraceptives</a> containing <a href="https://en.wikipedia.org/wiki/Ethinylestradiol" target="_blank">ethinylestradiol</a> can increase SHBG levels by 2- to 4-fold and decrease free testosterone concentrations by 40 to 80% in women."[<a href="https://books.google.com/books?id=aGDU5xibtNgC&pg=PA157" target="_blank">2</a>]</p><p></p><p>"Two hundred and fifty to 500 nmol/L 17 beta-estradiol and 500 nmol/L to 1 mumol/L testosterone increased SHBG levels intra- and extracellularly, but relative to control values, the increase was considerably greater inside the cells."[<a href="https://academic.oup.com/jcem/article-abstract/80/1/160/2650679?redirectedFrom=fulltext" target="_blank">3</a>]</p><p></p><p>"The secretion of sex hormone-binding globulin (SHBG) by the human hepatocarcinoma cell line Hep G2 was increased significantly ... by estradiol (E2)..."[<a href="https://academic.oup.com/jcem/article-abstract/64/4/825/2653888?redirectedFrom=fulltext" target="_blank">4</a>]</p></blockquote><p></p>
[QUOTE="Cataceous, post: 152390, member: 38109"] It is true in an absolute sense, as far as averages go. It's you who may be the exception. "Oral but not transdermal E2 increased SHBG concentrations by 67-171% in the control group..."[[URL='https://www.ncbi.nlm.nih.gov/pubmed/15784702']1[/URL]] "[URL='https://en.wikipedia.org/wiki/Oral_contraceptive']Oral contraceptives[/URL] containing [URL='https://en.wikipedia.org/wiki/Ethinylestradiol']ethinylestradiol[/URL] can increase SHBG levels by 2- to 4-fold and decrease free testosterone concentrations by 40 to 80% in women."[[URL='https://books.google.com/books?id=aGDU5xibtNgC&pg=PA157']2[/URL]] "Two hundred and fifty to 500 nmol/L 17 beta-estradiol and 500 nmol/L to 1 mumol/L testosterone increased SHBG levels intra- and extracellularly, but relative to control values, the increase was considerably greater inside the cells."[[URL='https://academic.oup.com/jcem/article-abstract/80/1/160/2650679?redirectedFrom=fulltext']3[/URL]] "The secretion of sex hormone-binding globulin (SHBG) by the human hepatocarcinoma cell line Hep G2 was increased significantly ... by estradiol (E2)..."[[URL='https://academic.oup.com/jcem/article-abstract/64/4/825/2653888?redirectedFrom=fulltext']4[/URL]] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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