L-glutamine, good or bad for the brain?

Gianluca

Well-Known Member
We could open a debate in the bodybuilding aspect of L-Glutamine if it is beneficial or not, I personally think it is, I like to take L-Glutamine first thing in the am after fasting all night for stopping muscle breakdown and after exercise, i use 3 to 5gr each time,

I recently started understating the L-glutamate factor, which G will be converted in, that it is an excitatory amino acid which it is bad long term for neurodegenerative disease and for people who have "mental disorders" like anxiety and panic attack. But the other hand G should be converted into GABA as well which is a great thing for the brain and anxiety/panic attacks , although I would highlight that it SHOULD convert, but I guess sometime under certain condition it does not, one that I'm aware of is Magnesium deficiency

I Have asked this my self cause as I first start using L-Glutamine, two years a go, I totally felt an anabolic state of mind and body and good muscle gain, which is great, so I kept using it, although I have history of anxiety and panic attack, and along with it I tend to get overexcited, and wondering when I go through these symptoms if G make them worse and I personally should avoid it??

Should I discontinue L-glutamine or just l keep its use of 2/5gr just after exercising? researches do show a decrease in L-Glutamine following exercise so I think it is wise to use it afterwords, plus the gut benefits

any other amino acid you guys would recommend to use in the am to stop muscle breakdown would not convert into Glutamate?

btw, according to Lifextention their recommended dose for gut health and sarcopenia prevention, which is 1000mg to 2000mg daily, won't interfere with L-glutamate at all
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
2
Guests online
372
Total visitors
374

Latest posts

Back
Top