Just Curious of AI need

Zooka15 · Mar 17, 2016

Hello all,
Been on TRT for awhile just switched to EOD Subq injections of 28mg, was doing 50MG 2x Week before. But I have been curious do most men need a AI and what is the optimal E2 range?

Thanks

Shawn

hfbjr · Mar 17, 2016

Why the switch from 2x a week to eod?

HoustonTX · Mar 17, 2016

Good question. Most people only switch to EOD if they are on higher than 100mgs per week to control estradiol. Zokka15, what do your labs say?

Vince · Mar 18, 2016

I believe you should measure it by symptoms, Nelson has a good post on Role of Estradiol in Men and Its Management https://www.excelmale.com/forum/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management

Zooka15 · Mar 18, 2016

I made the switch to EOD ,because I wanted to do sub q. The 50mg was causing a red spot on my skin, the lower dose seems to help with that side. My last estradiol reading was 31 on the lapcorp sensitive test. i notice sometimes I fluctuate in water weight and get flare ups of oily skin. Not sure if this is E2 related or not.

CoastWatcher · Mar 18, 2016

Zooka15 said:
I made the switch to EOD ,because I wanted to do sub q. The 50mg was causing a red spot on my skin, the lower dose seems to help with that side. My last estradiol reading was 31 on the lapcorp sensitive test. i notice sometimes I fluctuate in water weight and get flare ups of oily skin. Not sure if this is E2 related or not.

An estradiol level of 31 on the LC, MS/MS test is a comfortable result.

Zooka15 · Mar 18, 2016

That measurement was taken the day I am supposed to do my injection when I was doing 50mg x 2 week. So it it possible that it is was spiking a little higher. One of my biggest complaints on TRT is on and off erection quality. I am looking into switching to defy here in the near future.

hfbjr · Mar 18, 2016

Listening to everyones story/protocol and the various dilemas etc of finding the right dose kinda sucks.actually alot.i avent started yet,but i gotta admit its kinda unsettling

ERO · Mar 18, 2016

The 'rule of thumb' on AI is do not use one unless you have high E2 symptoms. In other words, do not start a protocol (as someone new to TRT) that includes an AI - start without an AI and only add it in if truly needed.

hfbjr · Mar 18, 2016

Even if you have symptoms or conditions(such as slight gyno,etc) prior to starting?wouldnt that make it worse once testosterone is introduced and levels go up.

ERO · Mar 18, 2016

Well, yes if you have gyno before you even start TRT and/or labs that show you have high E2 levels that means you have high E2 symptoms, which was the exception that I mentioned above.

hfbjr · Mar 18, 2016

Do many people start trt with these such symptoms or conditions?

Vince Carter · Mar 18, 2016

I think most that have labs before starting TRT seem an out-of-balance situation such as low T and High E that explains many of the low T symptoms.

hfbjr · Mar 18, 2016

I personally have a some gyno tgat has me worried,as well as high e symptoms

hfbjr · Mar 18, 2016

Gots me really nervous

ERO · Mar 18, 2016

Do you have any recent labs? You can get them without a prescription at http://www.discountedlabs.com/ the Pre-TRT MALE Hormone / Wellness Panel would be a good choice to get a solid baseline.

hfbjr · Mar 18, 2016

Yea,i had my labs forwarded to defy.my estroidal qas a 23,which wasnt the sensitive test.im awaitibg my lab results for the sensitive.i posted lab results few weeks back in the lab sect.
Main concern,as always ,is e issues.other than that,i cannot wait for treatment

ERO · Mar 18, 2016

Perfect. You are in great hands with Defy Medical!

CoastWatcher · Mar 18, 2016

hfbjr said:
Yea,i had my labs forwarded to defy.my estroidal qas a 23,which wasnt the sensitive test.im awaitibg my lab results for the sensitive.i posted lab results few weeks back in the lab sect.
Main concern,as always ,is e issues.other than that,i cannot wait for treatment

You certainly are in great hands with Defy. As a note, if your estradiol was 23 on the non-sensitive test, you are unlikely to have elevated estradiol at the present time. The standard test overestimates estradiol when it is used by men. But remember, estradiol is not something to be afraid of - it's a necessary hormone. To push it too low will leave you feeling miserable. The doctors at Defy will help you sort it out. All the best.