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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Issues with Testosterone Cream -- anyone else?
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<blockquote data-quote="S1W" data-source="post: 154182" data-attributes="member: 16947"><p>Yes'r - and both DHT and SHBG were higher on creams. I don't remember DHT numbers, but it was higher on cream. SHBG went down a few points switching to injections from cream - about 27 on cream down to 23 on injections.</p><p></p><p>Regarding E2 and thinking it through, E2 at its absolute peak would actually be higher on injections vs cream IF one is using the typical E3.5D or less frequent injection protocols because of the spike we get injecting larger doses. As I frequently see Vince Carter mention, we tend to test at trough on an injection protocol and E2 is actually higher at other times throughout the week than what we see when we do labs at trough. When I was playing around with my peak/trough labs on an injection protocol (60mg E3.5D), my peak TT was about 1480 and peak E2 was 54 about 24 hours after injection. A few days later at trough, TT was down to 880 and E2 down to 47. Again, that was with SHBG of 23.</p><p></p><p>For me, T cream peaks about about 4 hours, give or take, after application. In my experience with TC, peak occurs about 24 hours after injection. I have actually played with labs on consecutive days to confirm this. This may just be the case for me though, as I sometimes wonder whether we all cleave the ester off at different rates, or something to that effect...</p><p></p><p>It's worth noting that I do not have an apples to apples comparison as my cream dose was 100mg/week, dose applied daily. I do not have labs from a 100mg/week, daily injection protocol. I almost feel like that may be the only fair comparison.</p></blockquote><p></p>
[QUOTE="S1W, post: 154182, member: 16947"] Yes'r - and both DHT and SHBG were higher on creams. I don't remember DHT numbers, but it was higher on cream. SHBG went down a few points switching to injections from cream - about 27 on cream down to 23 on injections. Regarding E2 and thinking it through, E2 at its absolute peak would actually be higher on injections vs cream IF one is using the typical E3.5D or less frequent injection protocols because of the spike we get injecting larger doses. As I frequently see Vince Carter mention, we tend to test at trough on an injection protocol and E2 is actually higher at other times throughout the week than what we see when we do labs at trough. When I was playing around with my peak/trough labs on an injection protocol (60mg E3.5D), my peak TT was about 1480 and peak E2 was 54 about 24 hours after injection. A few days later at trough, TT was down to 880 and E2 down to 47. Again, that was with SHBG of 23. For me, T cream peaks about about 4 hours, give or take, after application. In my experience with TC, peak occurs about 24 hours after injection. I have actually played with labs on consecutive days to confirm this. This may just be the case for me though, as I sometimes wonder whether we all cleave the ester off at different rates, or something to that effect... It's worth noting that I do not have an apples to apples comparison as my cream dose was 100mg/week, dose applied daily. I do not have labs from a 100mg/week, daily injection protocol. I almost feel like that may be the only fair comparison. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Issues with Testosterone Cream -- anyone else?
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