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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is the feeling of "well being" on TRT, dosage dependent?
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<blockquote data-quote="John O'Connor" data-source="post: 184132" data-attributes="member: 13064"><p>Start low, and go slow. I agree with madman's advice to give it some time. It's good you started on a relatively conservative starting dose of 100mg per week, and that you are dosing 2x per week. My only concern with your initial post, and madman and others continued reference to labs done on your trough day, is that you really shouldn't have a change in levels while dosing every 3.5 days. Test cypionate peaks around 72 hours, and it's half life is about 8 days. Under this scenario, your trough day also happens to be your peak day. Technically the cypionate dose you injected 2 weeks ago is still about 25% active and it takes approximately 44 days to be completely eliminated from your body. Note, just like alcohol or any drug everyone's metabolism is unique. The beauty of dosing every 3.5 days or every other day is that you no longer need to worry about what day your lab work is done. For example I take 90mg weekly. Injecting 30mg Sunday morning, Tuesday night and Thursday night. No matter what day my labs are drawn, my total testosterone level is consistently around 700. I've never needed to use an AI. Note I also started on a higher dose, 100mg, 50mg twice weekly, I found it was too high. For me the best indicator that I'm on the best dose is morning wood frequency. If my dose is too high or too low I don't notice morning wood as frequently. I've never had nipple sensitivity issues, so I cannot speak to that. Individuals who dose once weekly are riding a roller coaster where their trough level at day 7 is probably 60 or 70 percent of their peak level at 72 hours. Check out drugs.com article called half-life explained. Just realize a drug taken orally with a 12 hour or 24 hour half life is dependent on how fast the liver metabolizes the drug. I hope this helps a little. *Note deleted the grapeseed and sesame seed references to half life.</p></blockquote><p></p>
[QUOTE="John O'Connor, post: 184132, member: 13064"] Start low, and go slow. I agree with madman's advice to give it some time. It's good you started on a relatively conservative starting dose of 100mg per week, and that you are dosing 2x per week. My only concern with your initial post, and madman and others continued reference to labs done on your trough day, is that you really shouldn't have a change in levels while dosing every 3.5 days. Test cypionate peaks around 72 hours, and it's half life is about 8 days. Under this scenario, your trough day also happens to be your peak day. Technically the cypionate dose you injected 2 weeks ago is still about 25% active and it takes approximately 44 days to be completely eliminated from your body. Note, just like alcohol or any drug everyone's metabolism is unique. The beauty of dosing every 3.5 days or every other day is that you no longer need to worry about what day your lab work is done. For example I take 90mg weekly. Injecting 30mg Sunday morning, Tuesday night and Thursday night. No matter what day my labs are drawn, my total testosterone level is consistently around 700. I've never needed to use an AI. Note I also started on a higher dose, 100mg, 50mg twice weekly, I found it was too high. For me the best indicator that I'm on the best dose is morning wood frequency. If my dose is too high or too low I don't notice morning wood as frequently. I've never had nipple sensitivity issues, so I cannot speak to that. Individuals who dose once weekly are riding a roller coaster where their trough level at day 7 is probably 60 or 70 percent of their peak level at 72 hours. Check out drugs.com article called half-life explained. Just realize a drug taken orally with a 12 hour or 24 hour half life is dependent on how fast the liver metabolizes the drug. I hope this helps a little. *Note deleted the grapeseed and sesame seed references to half life. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is the feeling of "well being" on TRT, dosage dependent?
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