Is the Cystatin- C Kidney Function Test Best for Muscular Men?

[style=font-size: medium;]Since the concentration of cystatin C in the blood will not change due to infection or inflammation and isn’t affected by body weight, drugs or diet - cystatin C level could be a more reliable indicator of kidney health than creatinine (2).[/style][style=font-size: medium;]
[/style]

[style=font-size: medium;]Testing for cystatin may also be useful to detect kidney disease early when the affected person isn’t experiencing many (if any) symptoms, and other test results are normal.[/style]

[style=font-size: medium;]What is Cystatin C?
[/style]


[style=font-size: medium;]Cystatin C is a protein found in almost all the cells in the body. Cystatin C helps to regulate the activity of enzymes needed to break down bigger molecules both inside of and around those cells (3).[/style]
[style=color: #282828;]Cystatin C level in the blood can be measured to determine how well the kidneys are functioning (3). The kidneys, liver, and spleen all work to filter the blood and excrete any waste substances as urine. This filtration process happens in a microscopic structure in the kidneys; the glomerulus (4). Each kidney contains approximately one-million glomeruli that function as tiny sieves to extract waste. The glomerular filtration rate (GFR) rate is a measure of how well the glomeruli are filtering blood (4).[/style]

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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