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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is long term HCG use detrimental?
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<blockquote data-quote="Jerry Brainum" data-source="post: 35815" data-attributes="member: 162"><p><strong>HCG long term</strong></p><p></p><p></p><p></p><p>My feeling is that you can stay on low-dose (no more than 500 iU a week) HCG indefinitely. I never found, nor heard of any evidence that using this dose range causes any type of problem. However, I have seen studies (I cannot supply specific names and journals) noting that extended use of HCG in larger doses of 1,000 iu or more causes the Leydig cells of the testes to become refractory to LH. In short, eventually when using larger doses continuously, the HCG simply won't work. Another study showed that extended use of HCG, again in larger doses, can cause oxidative damage to the Leydig cells. Apparently, this study (can't recall whether it was a human, in vitro, or animal study) also showed that ingesting supplemental NAC helped to prevent this effect. I know that the amino acid, taurine, in animal studies does offer antioxidant protection in the testes.</p></blockquote><p></p>
[QUOTE="Jerry Brainum, post: 35815, member: 162"] [b]HCG long term[/b] My feeling is that you can stay on low-dose (no more than 500 iU a week) HCG indefinitely. I never found, nor heard of any evidence that using this dose range causes any type of problem. However, I have seen studies (I cannot supply specific names and journals) noting that extended use of HCG in larger doses of 1,000 iu or more causes the Leydig cells of the testes to become refractory to LH. In short, eventually when using larger doses continuously, the HCG simply won't work. Another study showed that extended use of HCG, again in larger doses, can cause oxidative damage to the Leydig cells. Apparently, this study (can't recall whether it was a human, in vitro, or animal study) also showed that ingesting supplemental NAC helped to prevent this effect. I know that the amino acid, taurine, in animal studies does offer antioxidant protection in the testes. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Is long term HCG use detrimental?
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