Is HCG monotherapy sustainable? Is it worth spending the time and money trying to dial in a protocol?

For me, one major problem would be travel. HCG is difficult to travel with, and would mean it would be very difficult to travel for several weeks at a time around the world. So I never considered HCG monotherapy.
 
Besides what these guys are trying to be helpful with the first and foremost is that most all guys are Primary HypoGonadal, the problem is the testes. So, there's little reason to think that stimulating the testes with HCG mono level doses is going to result in much. It's much more likely in that scenario to get Estrogen production. If you could make your own T you likely wouldn't be in this situation to start with so it's just not logical to try it.
Guys that are secondary could have a reasonable response.
 
It depends. Are you trying to have children? Why are you thinking of mono therapy vs testosterone vs testosterone w/ HCG?
Fertility is important to me, but kids are still a few years away. I just feel more comfortable with my own body producing the testosterone if possible.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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