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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Is HCG enough to backfill pathways?
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<blockquote data-quote="tareload" data-source="post: 219597"><p>Yes, Pregnyl and other generics (Fresenius) are urinary derived. Thank those nice pregnant ladies in India or China. Your other option is Ovidrel or equivalent (see refererences above) which is recombinant.</p><p></p><p>I appreciate you sharing your experience.</p><p></p><p>I would agree that Pregnyl or Fresenius (I've used both) do their job well. I went to the trouble of diluting Ovidrel into a 5000 IU bottle (5000 IU per 5 mL) with bacteriostatic water and per normalized IU it never matched the same subjective or quantitative benefit of urinary derived hCG. I did this because u-hCG is a biologic soup even after chromatographic separation and the use of r-hCG addresses the potential risk of prion contamination.</p><p></p><p><a href="https://www.fertstert.org/article/S0015-0282(04)00553-9/fulltext" target="_blank">Epidermal growth factor contamination and concentrations of intact human chorionic gonadotropin in commercial preparations</a></p><p></p><p>[URL unfurl="true"]https://www.frontiersin.org/articles/10.3389/fendo.2019.00429/full[/URL]</p><p></p><p><strong>All compounded hCG in the US (now a moot point for the most part) was urinary derived </strong>and I personally never tried any of them. I'm kinda particular about my quality control with biologics. But hey, I've met MDs who have no problem injecting themselves with "research" peptides <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" />. FYI.</p></blockquote><p></p>
[QUOTE="tareload, post: 219597"] Yes, Pregnyl and other generics (Fresenius) are urinary derived. Thank those nice pregnant ladies in India or China. Your other option is Ovidrel or equivalent (see refererences above) which is recombinant. I appreciate you sharing your experience. I would agree that Pregnyl or Fresenius (I've used both) do their job well. I went to the trouble of diluting Ovidrel into a 5000 IU bottle (5000 IU per 5 mL) with bacteriostatic water and per normalized IU it never matched the same subjective or quantitative benefit of urinary derived hCG. I did this because u-hCG is a biologic soup even after chromatographic separation and the use of r-hCG addresses the potential risk of prion contamination. [URL='https://www.fertstert.org/article/S0015-0282(04)00553-9/fulltext']Epidermal growth factor contamination and concentrations of intact human chorionic gonadotropin in commercial preparations[/URL] [URL unfurl="true"]https://www.frontiersin.org/articles/10.3389/fendo.2019.00429/full[/URL] [B]All compounded hCG in the US (now a moot point for the most part) was urinary derived [/B]and I personally never tried any of them. I'm kinda particular about my quality control with biologics. But hey, I've met MDs who have no problem injecting themselves with "research" peptides :). FYI. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Is HCG enough to backfill pathways?
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