Intramuscular injections and hematocrit

  • Thread starter Thread starter Palermitano
  • Start date Start date
All forms of TRT increase hematocrit.

These factors that tend to affect hematocrit:

1- Dose (testosterone peaks)
3- Genetics
4- Length of treatment (hematocrit can stabilize after 12-18 months on TRT)
5- Age (younger men tend to have larger hematocrit increases)
6- DHT seems to be the metabolite with the biggest effect on hematocrit
 
DHT having the biggest effect on Hematocrit seems strange considering transdermal testosterone supposedly increases DHT more than IM? I've only tested my DHT once, after being on TRT for a while (unfortunately no baseline), and it was out of range to the high side. I have not continued to test it because I'm not sure what to do about it. I am benefiting greatly from TRT and am unwilling to take any of the prescription 5AR blockers due to the prevalence of side effects which can continue after ceasing the medication. Maybe this should be a new thread but does anyone have any advise for dealing with high DHT? Of note I am 50 years old and am bald/shaved head and have no prostate issues.
Is high DHT in and of itself a problem?
 
...oh and i give blood every 56 days due to my hematocrit being in the 50 - 51% range when i don't. I know that this is seen as an ok number by some but my doctor doesn't like it reaching 50%.
 
DHT having the biggest effect on Hematocrit seems strange considering transdermal testosterone supposedly increases DHT more than IM? I've only tested my DHT once, after being on TRT for a while (unfortunately no baseline), and it was out of range to the high side. I have not continued to test it because I'm not sure what to do about it. I am benefiting greatly from TRT and am unwilling to take any of the prescription 5AR blockers due to the prevalence of side effects which can continue after ceasing the medication. Maybe this should be a new thread but does anyone have any advise for dealing with high DHT? Of note I am 50 years old and am bald/shaved head and have no prostate issues.
Is high DHT in and of itself a problem?

Elevated DHT does not pose any real health problems but it can have some negative side effects in some men like male pattern baldness.

DHT is converting from Testosterone by the 5 alpha reductase enzyme that largely resides in adipose tissue and why men on TD's convert higher to DHT then men on IM.

DHT is 7 to 10 time more androgenic then Testosterone and is what makes us a man...and it really drive libido as well.

Unless you are presenting with negative sides I wouldn't worry about elevated DHT...just hit the gym and take advantage of it!!!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
6
Guests online
1,604
Total visitors
1,610

Latest posts

Back
Top