Infections, antimicrobial stewardship and PCa detection: TP vs TRUS prostate biopsy

madman

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A balance among infections, antimicrobial stewardship and prostate cancer detection: TP vs TRUS prostate biopsy


Prostate biopsies are the key step to diagnose prostate cancer and one of the most performed procedures in urology. The biopsy can be performed either the trans-perineal (TP) way or via trans-rectal ultrasound (TRUS). While these procedures have the same diagnostic power, the discussions on which approach is the best for infectious complications are controversial.

Due to the rising antibiotic resistance rates worldwide, tackling further resistance development is essential. In this recording, we will discuss the optimal way to overcome resistance development for prostate biopsy and underline the importance for antimicrobial stewardship (ABS).
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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