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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Individualized differences based on carrier oils used for Test Cyp?
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<blockquote data-quote="rifter" data-source="post: 213866" data-attributes="member: 14772"><p>Has anyone done a blood test comparison between using grapeseed and cottonseed oil based testosterone cypionate?</p><p></p><p>Some time ago, I used a bottle of Wilshire testosterone cypionate which (and I would love someone to confirm this) I believe was cottonseed oil based. This was sold to me by my compounding pharmacy as they were short of their own product at the time. They referred to this as "commercial" or "retail" if memory serves.</p><p></p><p>My bloodwork was perfect - Great Total & Free T, solid E2, excellent hematocrit and hematology. To top it off, I remember feeling really good, so much so, I kept the box around for a number of months so I could remember the name.</p><p></p><p>I then went back to my normal grapeseed compounded testosterone cypionate. Total & Free T was erratic, sometimes over, sometimes well under the high-end, horrible hematocrit and slightly higher E2 levels (to the point where my doc actually suggested I start using an AI again) and generally don't feel as good. Dosage didn't change.</p><p></p><p>I'm thinking this could either be:</p><p>1) completely placebo</p><p>2) differing absorption or dispersion rates between grapeseed and cottonseed (is this even a thing?)</p><p>3) my body simply utilizes cottonseed oil differently than grapeseed</p><p></p><p>I'm also aware that more frequent administration (like EOD vs. twice weekly) has been noted by some individuals to better control hematocrit and E2 at the same weekly dosage.</p><p></p><p>My thought is that if this is due to the way someone metabolizes the carrier oil, then many of the side-effects people experience (like the hematocrit or high E2 symptoms) could also be controlled through carrier oil selection as a consideration, in addition to changing frequency of administration, lowering the dose or changing the ester etc.</p><p></p><p>There must also be some research indicating why pharmaceutical/retail versions use cottonseed oil instead of another carrier oil.</p><p></p><p>I'd be interested if anyone has any thoughts on this or has done research on different carriers, or otherwise has recent experience between switching from branded Test C using cottonseed, to compounded Test C using grapeseed?</p></blockquote><p></p>
[QUOTE="rifter, post: 213866, member: 14772"] Has anyone done a blood test comparison between using grapeseed and cottonseed oil based testosterone cypionate? Some time ago, I used a bottle of Wilshire testosterone cypionate which (and I would love someone to confirm this) I believe was cottonseed oil based. This was sold to me by my compounding pharmacy as they were short of their own product at the time. They referred to this as "commercial" or "retail" if memory serves. My bloodwork was perfect - Great Total & Free T, solid E2, excellent hematocrit and hematology. To top it off, I remember feeling really good, so much so, I kept the box around for a number of months so I could remember the name. I then went back to my normal grapeseed compounded testosterone cypionate. Total & Free T was erratic, sometimes over, sometimes well under the high-end, horrible hematocrit and slightly higher E2 levels (to the point where my doc actually suggested I start using an AI again) and generally don't feel as good. Dosage didn't change. I'm thinking this could either be: 1) completely placebo 2) differing absorption or dispersion rates between grapeseed and cottonseed (is this even a thing?) 3) my body simply utilizes cottonseed oil differently than grapeseed I'm also aware that more frequent administration (like EOD vs. twice weekly) has been noted by some individuals to better control hematocrit and E2 at the same weekly dosage. My thought is that if this is due to the way someone metabolizes the carrier oil, then many of the side-effects people experience (like the hematocrit or high E2 symptoms) could also be controlled through carrier oil selection as a consideration, in addition to changing frequency of administration, lowering the dose or changing the ester etc. There must also be some research indicating why pharmaceutical/retail versions use cottonseed oil instead of another carrier oil. I'd be interested if anyone has any thoughts on this or has done research on different carriers, or otherwise has recent experience between switching from branded Test C using cottonseed, to compounded Test C using grapeseed? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Individualized differences based on carrier oils used for Test Cyp?
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