madman
Super Moderator
CONCLUSION
Given the increasing evidence for the salutary effects of combined beta-blockade of burn-related hypermetabolism and the use of anabolic agents to blunt catabolism and increase anabolism, we conclude that the long-term administration of oxandrolone with propranolol should be considered for the treatment of pediatric burn survivors. The benefits of this combined treatment strategy, including resumed growth, increased muscle mass, greater strength, and now reduction in scar and greater activity, suggest that OxProp may be the most efficacious modulator of the hypermetabolic response that we have tested in burned children. Although long-term treatment of burned adults with oxandrolone has not been trialed, our reports of beneficial effects of OxProp suggest that this combination should be trialed in adults as well.
Given the increasing evidence for the salutary effects of combined beta-blockade of burn-related hypermetabolism and the use of anabolic agents to blunt catabolism and increase anabolism, we conclude that the long-term administration of oxandrolone with propranolol should be considered for the treatment of pediatric burn survivors. The benefits of this combined treatment strategy, including resumed growth, increased muscle mass, greater strength, and now reduction in scar and greater activity, suggest that OxProp may be the most efficacious modulator of the hypermetabolic response that we have tested in burned children. Although long-term treatment of burned adults with oxandrolone has not been trialed, our reports of beneficial effects of OxProp suggest that this combination should be trialed in adults as well.
