MK677 is a ghrelin receptor agonists like the GHRP's. Ghrelin is the hunger hormone so MK677 stimulates the hunger hormone, ghrelin. We all react differently to MK677 when it comes to hunger. So, some get very hungry, some don't. I never got hungry taking MK nor did I ever get hungry using any of the GHRPs.The biggest difference I would say is the quality control. Even though it may be a reputable online peptide company, there are not quality control standards that will ensure what you are getting is what is on the label. There is a very good chance the product will be overdosed/under-dosed. If you are able to obtain it from a pharma company, then why not get it that way?
Additionally, what reason are you looking into MK677. I am just curious on your thoughts. I was looking into it as well but my igf levels are within normal limits and after a lot of research, I noticed that a lot of people complain about the uncontrollable hunger. I am hungry enough and don't need another reason to eat. lol.
Let me know your thoughts.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038