I started with oral TRT with Maximus last week. I have a couple of questions....

[busydad]

They prescribed me 600mg taken in the morning with 30-50g of fat.

Should I be dividing this dose into 300mg 2x per day? In the morning and then around 12:00? Or should I just stick with the 600mg in the morning.

I usually take it with walnuts or pecans. I have read that I should take the dose about 30 minutes after my meal, not with may meal. Any benefit to this?

After the medication has worn off 6-12 hours from what I read, will my levels be back at baseline, as if I hadn't taken the medication or will they stay somewhat elevated?

Thanks for helping.

 

[FunkOdyssey]

I work for Maximus and can answer some of these questions for you.

Should I be dividing this dose into 300mg 2x per day? In the morning and then around 12:00? Or should I just stick with the 600mg in the morning.

90% of patients stick with a single morning dose. 10% prefer to split the dose, and take some amount of it a bit later in the afternoon. If you're curious to try splitting the dose, reach out to your Maximus provider and they'll work with you to experiment with that.

I usually take it with walnuts or pecans. I have read that I should take the dose about 30 minutes after my meal, not with may meal. Any benefit to this?

The idea here is for the testosterone to reach the small intestine when chylomicrons are actively being formed to absorb the dietary fat, so the testosterone can hitch a ride. If you find the 30 minute delay after the meal difficult to be consistent with, don't worry about it, and just take the testosterone when you finish the meal. The difference in bioavailability, if any, should be minor.

After the medication has worn off 6-12 hours from what I read, will my levels be back at baseline, as if I hadn't taken the medication or will they stay somewhat elevated?

Your levels will not remain elevated after the oral testosterone has been metabolized, but it is not necessary for levels to be elevated 24 hours a day to reap the benefits of TRT. The way you feel has as much or more to do with long-term TRT-driven changes in gene expression than moment-to-moment changes in serum levels.

 

[busydad]

I work for Maximus and can answer some of these questions for you.


90% of patients stick with a single morning dose. 10% prefer to split the dose, and take some amount of it a bit later in the afternoon. If you're curious to try splitting the dose, reach out to your Maximus provider and they'll work with you to experiment with that.


The idea here is for the testosterone to reach the small intestine when chylomicrons are actively being formed to absorb the dietary fat, so the testosterone can hitch a ride. If you find the 30 minute delay after the meal difficult to be consistent with, don't worry about it, and just take the testosterone when you finish the meal. The difference in bioavailability, if any, should be minor.


Your levels will not remain elevated after the oral testosterone has been metabolized, but it is not necessary for levels to be elevated 24 hours a day to reap the benefits of TRT. The way you feel has as much or more to do with long-term TRT-driven changes in gene expression than moment-to-moment changes in serum levels.

@FunkOdyssey

My meal usually consists of a couple handful of walnuts or pecans, as I usually do not eat breakfast and I'm never really hungry in the morning. Is this sufficient?

I've been thinking about moving my dose to 12:00 noon. My bedtime is usually 11:00 pm, and I'm rising at 7:00 am. Do you see any concerns with moving the dose to 12:00 noon?

 

[FunkOdyssey]

My meal usually consists of a couple handful of walnuts or pecans, as I usually do not eat breakfast and I'm never really hungry in the morning. Is this sufficient?

Sounds like 35 - 40 grams of fat, which should be sufficient.

I've been thinking about moving my dose to 12:00 noon. My bedtime is usually 11:00 pm, and I'm rising at 7:00 am. Do you see any concerns with moving the dose to 12:00 noon?

No, but communicate with your provider before making any adjustments to your protocol.