I need ARUP Labs Estradiol Sensitive number.

Can someone clarify which test I should use? Doctor could not find "sensitive" version and asked me to specify which test. It looks like ARUP labs is their preferred provider.

http://ltd.aruplab.com/

1.2006160Free Estradiol by ED/LC-MS/MS
Ordering Recommendation: Direct measure of free estradiol in serum. Most accurate measure of bioactive estradiol.
2.0070045Estradiol, Adult Premenopausal Female, Serum or Plasma
Ordering Recommendation: Suitable for measurement of estradiol in adult premenopausal women. In all other groups, the preferred test is Estrogens, Fractionated by Tandem Mass Spectrometry (HPLC) test (0093248).
3.0093247Estradiol, Males, Children or Postmenopausal Females by Tandem Mass Spectrometry
Ordering Recommendation: Suitable for measurement of estradiol in men, children, or postmenopausal women. Preferred test for adult premenopausal women is Estradiol, Adult Premenopausal Female, Serum or Plasma (0070045).
4.0093248Estrogens, Fractionated by Tandem Mass Spectrometry
Ordering Recommendation: Recommended test for evaluating endogenous estrogen status in postmenopausal women, men, or children.
5.0099375Sex Hormone Binding Globulin
... Testosterone-Estradiol Binding Globulin ... Testosterone-Estradiol Binding Globulin (TeBG) ...
 
That makes sense. Not only does it mention it is for males (where the first 2 probably are not) - it also mentions Tandem Mass Spectrometry as the methodology, and that's what it says in small print on my latest LabCorp test results. It says this exactly:
"Methodology: Liquid chromatography tandem mass spectrometry (LC/MS/MS)"
 
We always say LC/MS/MS is the test to have...sometimes across labs Sensitive and UltraSensitive seem to be interchangeable terms. Of those listed I would select #3 that states for males though I've not heard of Tandem Mass Spectrometry, sounds close to our LC/MS/MS (which is mass spectrometry).

Test one has the marker LC/MS/MS but the "Free Estradiol" is throwing me off of it.
 
That makes sense. Not only does it mention it is for males (where the first 2 probably are not) - it also mentions Tandem Mass Spectrometry as the methodology, and that's what it says in small print on my latest LabCorp test results. It says this exactly:
"Methodology: Liquid chromatography tandem mass spectrometry (LC/MS/MS)"

Thanks for pointing that out.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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